Results 201 to 210 of about 6,273 (246)

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky   +5 more
wiley   +1 more source

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Treatment Strategies Targeting Persister Cell Formation in Bacterial Pathogens

open access: yesCritical Reviews in Microbiology, 2020
Persister cells are transiently antibiotic-tolerant and dormant subpopulations that are produced to escape the effects of antibiotics within biofilms or planktonic cell populations.
Young-Mog Kim   +2 more
exaly   +2 more sources

Persistent Persister Misperceptions [PDF]

open access: yesFrontiers in Microbiology, 2016
Persister cells survive antibiotic treatment due to their lack of metabolism, rather than through genetic change, as shown via four seminal experiments conducted by the discoverers of the phenotype (Hobby et al., 1942; Bigger, 1944). Unfortunately, over seven decades of persister cell research, the literature has been populated by misperceptions that ...
Thomas K. Wood, Jun-Seob Kim
exaly   +3 more sources
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Persistent Summaries

ACM Transactions on Database Systems, 2022
A persistent data structure , also known as a multiversion data structure in the database literature, is a data structure that preserves all its previous versions as it is updated over time.
Tianjing Zeng   +5 more
openaire   +3 more sources

Drug-Tolerant Persister Cancer Cells Are Vulnerable to GPX4 Inhibition [PDF]

open access: yesNature, 2017
Cancer persister cells, which survive cytotoxic treatments, are shown to be sensitive to inhibition of the lipid hydroperoxidase ...
Vasanthi S Viswanathan   +2 more
exaly   +2 more sources

To persist or not to persist?

Nonlinearity, 2004
Summary: Ecological vector fields \(\dot x_j= x_if_i(x)\) on the nonnegative cone \(\mathbb{R}^n_+\) on \(\mathbb{R}^n\) are often used to describe the dynamics of \(n\) interacting species. These vector fields are called permanent (or uniformly persistent) if the boundary \(\partial\mathbb{R}^n_+\) of the nonnegative cone is repelling. We construct an
Hofbauer, Josef, Schreiber, Sebastian J.
openaire   +1 more source

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