Results 51 to 60 of about 49,609 (300)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Institutional Betrayal, Psychoanalytic Insights on the Anglican Church’s Response to Abuse

open access: yesReligions, 2022
Psychoanalysis can advance our understanding of responses from the hierarchy of mainstream religious denominations to disclosures of abuse by clergy.
Fiona Gardner
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Processing Reflexes of the Feature Hierarchy (Person>Number>Gender) and implications for linguistic theory

open access: yes, 2005
Carminati MN. Processing Reflexes of the Feature Hierarchy (Person>Number>Gender) and implications for linguistic theory. Lingua.
Maria Nella Carminati   +1 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Argument marking and hierarchy effects: why Jivaroan is a special case [PDF]

open access: yes, 2014
[Extract] Differential object marking (DOM) has been described as a phenomenon by which a language marks case overtly on some direct objects but not on others depending on the semantic and pragmatic features of the object (Bossong 1985, 1991; Aissen 2003)
Overall, Simon, Kohlberger, Martin
core  

Group dominance in hierarchy-attenuating and hierarchy-enhancing organizations: The role of social dominance orientation, need for cognitive closure, and power tactics in a person–environment (mis)fit perspective

open access: yes, 2020
We examined, in different work organizations, how subordinates high in social dominance orientation (SDO; individual desire to sustain group-based hierarchies) and in need for cognitive closure (NFCC, an individual's epistemic motivation to avoid ...
Pratto, Felicia   +3 more
core   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Person-Organization Congruence and the Maintenance of Group-Based Social Hierarchy: A Social Dominance Perspective [PDF]

open access: yes, 2011
Using vocational choice theory and social dominance theory as guiding frameworks, this paper examines the interrelationships between the types of social institutions that a person occupies, on the one hand, and the ...
Sidanius, Jim, Haley, Hillary
core   +1 more source

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