Results 51 to 60 of about 27,770 (259)

Toward the Quadruple Aim

open access: yesMayo Clinic Proceedings: Innovations, Quality & Outcomes, 2020
Objective: To assess the effect of a faculty development program (Mentoring and Professionalism in Training [MAP-IT]) that fosters humanism in medicine on elements of burnout and the development of resilience.
Andrew W. Menzin, MD, MBA   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Research on the influence mechanism of organizational management pressure and salary satisfaction on miners’ job burnout

open access: yesMeikuang Anquan
In order to reduce miners’ unsafe behaviors, effectively prevent coal mine accidents, and ensure production safety, a theoretical hypothesis model was constructed to examine the relationships among organizational management pressure, salary satisfaction,
Shuicheng TIAN   +4 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Occupational Burnout in the Operating Room Staff in Teaching Hospitals: Affiliated Isfahan University of Medical Sciences in 2016

open access: yesپیاورد سلامت, 2018
Background and Aim: The personnelchr('39')s of the operating room due to many contacts with patients are exposed to stress, which ultimately leads to burnout.
Mahmood Keyvanara   +2 more
doaj  

Academic burnout and its mental health correlates among veterinary nursing students in Ghana: A cross-sectional study

open access: yesJournal of Affective Disorders Reports
This study explored the prevalence and risk factors of academic burnout among veterinary nursing students in Ghana.A cross-sectional online survey was conducted among students in the veterinary nursing program.
Godwin Dogbey   +8 more
doaj   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine   +40 more
wiley   +1 more source

Relationship of Organizational Commitment with Job Burnout and Organizational Spirituality between Zahedan and Gorgan Post Office Employees [PDF]

open access: yesپژوهش‌های مدیریت عمومی, 2012
The purpose of the present study was to ascertain the relationship of organizational commitment with job burnout and organizational spirituality between Zahedan and Gorgan post office employees. The sample size consisted of 200 post office employees (100
doaj   +1 more source

Community experience and personal accomplishment in Alcoholics Anonimous: a phenomenological research

open access: yesSMAD. Revista Eletrônica Saúde Mental Álcool e Drogas (Edição em Português), 2016
Objetivamos compreender como os sujeitos que se autorrealizam em Alcoólicos Anônimos (A.A.) vivenciam a experiência comunitária nesse contexto e como essa experiência se associa à realização e formação pessoal. Realizamos entrevistas com quatro participantes de A.A., cujos dados foram analisados fenomenologicamente.
Ana Cláudia Bernardes Guimarães   +1 more
openaire   +2 more sources

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