Results 91 to 100 of about 591,971 (351)

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

The construct validity of the Dutch personality inventory for DSM-5 personality disorders (PID-5) in a clinical sample [PDF]

, 2015
The factor structure and the convergent validity of the Personality Inventory for DSM-5 (PID-5), a self-report questionnaire designed to measure personality pathology as advocated in the fifth edition, Section III of Diagnostic and Statistical Manual of ...
Bastiaens, Tim, Claes, Laurence, Claes, Stephan, De Clercq, Barbara, De Fruyt, Filip, De Hert, Marc, Dirk, Smits, Lowyck, Benedicte, Rossi, Gina, Vanwalleghem, Dominique, Vermote, Rudi   +10 more
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Clinical importance of personality difficulties : diagnostically sub-threshold personality disorders [PDF]

, 2017
Background: Current categorical classification of personality disorders has been criticized for overlooking the dimensional nature of personality and that it may miss some sub-threshold personality disturbances of clinical significance.
Horjamo, Kalle, Karukivi, Max, Korkeila, Jyrki, Nevalainen, Minna, Vahlberg, Tero   +4 more
core   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Designing a range of mentalizing interventions for young people using a clinical staging approach to borderline pathology

Borderline Personality Disorder and Emotion Dysregulation, 2020
Borderline personality disorder (BPD) can have a long-lasting impact on social and professional functioning, even when core symptoms of BPD are in remission.
Joost Hutsebaut, Martin Debbané, Carla Sharp   +2 more
doaj   +1 more source

Does every psychopath have an antisocial personality disorder? [PDF]

, 2020
Elias Abdalla-Filho, Birgit Vӧllm
openalex   +1 more source

Is Criminal Sentencing Influenced by Type of Disorder?

, 2019
Differences in sentencing due to disorder and gender were examined. Four scenarios were randomly presented for each disorder type. Participants indicated the sentence length for each scenario and whether they would parole the individual.
Jones, Tessa, Koch, Christopher
core  

Mental health problems: Are they or are they not a risk factor for dropout from drug treatment? A systematic review of the evidence [PDF]

, 2009
Background: A sizeable number of recent studies investigating whether clients with substance misuse and mental health problems (dual diagnosis clients) are at heightened risk of dropout from drug treatment have been published.
Broome KM, Christine Barrowclough, Crawford V, Goldstein MF, Gossop M, Gossop M, Lewin TJ, Martinez-Raga J, Petra S. Meier, Ross HE, Schulte S   +10 more
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source