Results 81 to 90 of about 181,657 (309)

Preface to Personality and Brain Disorders: Associations and Interventions

, 2019
The human brain, the body’s control center, is composed of billions of glia, 100 billion neurons, and one quadrillion neural connections. The brain is part of the nervous system, which also includes the spinal cord and a large network of peripheral ...
Archer, Trevor,, Kostrzewa, Richard M., Garcia, Danilo,   +2 more
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Prevalence of the alternative model of personality disorders diagnoses in populational and at-risk samples, gender and age groups comparisons, and normative data for the LPFS-SR and PID-5.

, 2023
: The Alternative Model of Personality Disorders (AMPD), introduced in Section III of the DSM-5 (APA, 2013), was proposed as a new operationalization of personality disorders (PD) aiming to overcome the several limitations of the traditional symptom ...
Mélanie Lapalme, Le Corff, Yann, Morin, Rosalie, Rivard, Geneviève, Lapalme, Mélanie, Geneviève L'Ecuyer, Geneviève Rivard, Jean-Pierre Rolland, Forget, Karine, Rosalie Morin, Yann Le Corff, Karine Forget, L'Ecuyer, Geneviève   +12 more
core   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Personality in men with eating disorders

, 2004
OBJECTIVE: This study compares personality variables of men with eating disorders to women with eating disorders. METHOD: Data were obtained from an international study of the genetics of eating disorders.
KAPLAN AS, BERRETTINI WH, BACANU SA, TOZZI F, ROTONDO A, GANJEI K, DEVLIN B, KLUMP KL, FICHTER MM, KAYE W.H., CROW S, PERSONALITY IN MEN WITH EATING DISORDERS, BULIK CM, MITCHELL J, KEEL P, THORNTON L, STROBER M, CASSANO G, WOODSIDE DB, HALMI KA, MAURI, MAURO   +20 more
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Bipolar disorder and personality disorder

European Psychiatry, 2003
Patients with bipolar disorders experience cyclical changes in mood that present as a range of different syndromes. In classical mania, patients experience episodes of euphoria, whereas in depressive episodes they suffer from depression. In hypomania, patients experience a milder form of mania, and in mixed mania, patients may experience both manic and
Charles, Bowden, Wolfgang, Maier
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Psychiatrists' Perspectives on Prescription Decisions for Patients With Personality Disorders

There is currently insufficient evidence for the use of a specific pharmacological treatment for personality disorders (PD). The research literature lacks a systematic exploration of clinicians' experiences of pharmacological treatment of PD.
Di Leone, Flavio,, Kollia, Sofia, Sand, Peter,, Dervisoski, Evelina, Strand, Jennifer,   +4 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Personality disorders

, 2009
This chapter explains the main categories of personality disorders and their diagnosis.Nursing interventions are described, and challenges working with people who have personality disorders are discussed.Limitations in our understanding of personality ...
Farrell, Gerry, Campbell, Christina
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