Ciliary Membrane Lipid Homeostasis in Health and Disease
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang +3 more
wiley +1 more source
Development and validation of a machine learning-based model for predicting live birth outcomes in patients undergoing frozen-thawed embryo transfer. [PDF]
Luo S, Wang D.
europepmc +1 more source
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Perfusion Cell Cultures: Is the Technology Worthwhile for Biopharmaceutical Production?
The biotechnology industry is pursuing innovation and robust production, yet many biopharmaceuticals are manufactured from batch or fed‐batch cell cultures. Perfusion processes, offering higher yields and efficiency, remain underused despite their maturity.
Francesco Iannacci, Mattia Sponchioni
wiley +1 more source
A novel approach to treating Endometriosis-Related Repeated IVF failures- insights from single case report. [PDF]
Orvieto R.
europepmc +1 more source
ABSTRACT Background Adolescent and young adult childhood cancer survivors (AYA‐CCS) face elevated risks of chronic health conditions and premature mortality further exacerbated by poor lifestyle behaviors including physical inactivity, poor nutrition, and substance use.
C. Gélinas‐Gagné +11 more
wiley +1 more source
Case Report: Sequential blastocyst transfer for women with unexplained recurrent implantation failure: a case series. [PDF]
Yin P, Wu Y, Jiang M, Li Y.
europepmc +1 more source
Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha +4 more
wiley +1 more source
This review summarises how spatial transcriptomics technologies reveal tumour microenvironment heterogeneity and support the inference of dynamic remodelling during cancer progression. Abstract Background Spatiotemporal transcriptomics (STT) integrates spatially resolved gene expression with temporal information derived from staged samples, paired ...
Ying Kang +9 more
wiley +1 more source
Endometriosis-Associated Implantation Failure: Pathophysiology, Biomarkers, and Emerging Therapeutic Strategies. [PDF]
Sarli V +4 more
europepmc +1 more source

