Non-Invasive and Mechanism-Based Molecular Assessment of Endometrial Receptivity During the Window of Implantation: Current Concepts and Future Prospective Testing Directions [PDF]
Suboptimal endometrial receptivity and altered embryo-endometrial crosstalk account for approximately two-thirds of human implantation failures. Current tests of the window of implantation, such as endometrial thickness measurements and the endometrial ...
Bei Sun, John Yeh
doaj +4 more sources
MicroRNA signatures in plasma and plasma exosome during window of implantation for implantation failure following in-vitro fertilization and embryo transfer [PDF]
Background MicroRNAs (miRNAs) are small, non-coding RNAs that are dysregulated in many diseases and can act as biomarkers. Although well-studied in cancer, the role of miRNAs in embryo implantation is poorly understood.
Hong Zeng, Yu Fu, Lang Shen, Song Quan
doaj +2 more sources
Comparative evaluation of NOTCH signaling molecules in the endometrium of women with various gynecological diseases during the window of implantation [PDF]
Objective(s): NOTCH signaling pathway is well known for its role in cell fate, cell survival, cell differentiation, and apoptosis. Some of the NOTCH signaling genes are critical for endometrial function and implantation in animals and appear to play a ...
Fatemeh sadat Amjadi +7 more
doaj +2 more sources
Endometrial MicroRNA Signature during the Window of Implantation Changed in Patients with Repeated Implantation Failure [PDF]
Background: At present, a diagnostic tool with high specificity for impaired endometrial receptivity, which may lead to implantation failure, remains to be developed.
Cheng Shi +11 more
doaj +2 more sources
Altered Endometrial Memory T-Cell Profiles During the Window of Implantation in Women with Previous Miscarriage [PDF]
Aim: This study aimed to characterize and compare the composition of central (TCM), effector (TEM), tissue-resident (TRM), and terminally differentiated (TEMRA) memory T cells in mid-luteal endometrium during the window of implantation (WOI) in women ...
Dimitar Parvanov +8 more
doaj +2 more sources
Polycystic ovary syndrome (PCOS) is a common disorder with wide-ranging clinical heterogeneity that causes infertility. However, the comprehensive molecular mechanisms of PCOS in causing infertility is remaining unclear. Hence, a comprehensive literature
Zulazmi Sutaji +5 more
doaj +3 more sources
Clinical applications of endometrial receptivity tests in patients with recurrent implantation failure [PDF]
Recurrent implantation failure is represented by the failure to achieve a clinical pregnancy after transfer of at least 4 good-quality embryos in a minimum of 3 fresh or frozen cycles in a woman under the age of 40 years.
Ioan BOLEAC +5 more
doaj +1 more source
Background: Our aim in this study was to evaluate whether endometrial receptivity assay (ERA) test improves single, autologous euploid frozen-thawed embryo transfer (FET) outcomes in patients with repeated implantation failure.
Selin Ozaltin +7 more
doaj +1 more source
Objective. Vascular endothelial growth factor (VEGF) is a well-known angiogenic factor that is essential to numerous physiological and pathological processes.
Rui Jin +5 more
doaj +1 more source
Background: Repeated implantation failure (RIF) affects 15% of women of reproductive age. There is a high endometrial expression of both estrogen receptors and progesterone receptors (PRs) during the window of implantation in women with RIF.
Fattaneh Farifteh +9 more
doaj +1 more source

