Results 21 to 30 of about 174,551,336 (290)

Uterine ALK3 is essential during the window of implantation. [PDF]

Proc Natl Acad Sci U S A, 2016
Significance In the assisted reproductive technology (ART) clinic, pregnancy is defined by the rise of human chorionic gonadotropin upon embryo implantation. Achieving embryo implantation is a major roadblock to the success of ART; it is estimated that only 50% of transferred embryos implant in patients seeking ART, and that half of ...
Monsivais D, Clementi C, Peng J, Titus MM, Barrish JP, Creighton CJ, Lydon JP, DeMayo FJ, Matzuk MM.   +8 more
europepmc   +4 more sources

Clinical relevance of a newly developed endometrial receptivity test for patients with recurrent implantation failure in Japan

Reproductive Medicine and Biology, 2022
Purpose To assess the clinical efficacy of personalized embryo transfer (pET) guided by a new endometrial receptivity test, ERPeakSM, in patients with recurrent implantation failure (RIF).
Yasuhiro Ohara, Hidehiko Matsubayashi, Yosuke Suzuki, Yukiko Takaya, Kohei Yamaguchi, Masakazu Doshida, Takumi Takeuchi, Tomomoto Ishikawa, Mika Handa, Tatsuya Miyake, Tsuyoshi Takiuchi, Tadashi Kimura   +11 more
doaj   +1 more source

A Hand to Support the Implantation Window [PDF]

Science, 2011
A signaling pathway connects ovarian hormones to preparation of the mammalian uterus for pregnancy.
Sylvia C, Hewitt, Kenneth S, Korach
openaire   +2 more sources

Endometrial receptivity tests in reproduction: a SWOT analysis

AJOG Global Reports, 2023
Endometrial receptivity and its management in assisted reproduction is now a significant focus of research interest. Endometrial receptivity tests, which analyze different panels of gene expression, are usually offered in fertility clinics to determine ...
Juan A. Garcia-Velasco, MD, PhD, Joaquín Llácer, MD, PhD, Antonio Requena, MD, PhD, Miguel Ángel Checa, MD, PhD, José Bellver, MD, PhD, Ernesto Bosch, MD, PhD, Juan José Espinós, MD, PhD, Francisco Fabregues, MD, PhD, Ana Isabel Ortega, PharmD, PhD, Juan Fontes, MD, PhD   +9 more
doaj   +1 more source

Altered endometrial oestrogen-responsiveness and recurrent reproductive failure

Reproduction and Fertility, 2022
Recurrent reproductive failure (RRF) encompasses recurrent implantation failure (RIF) and recurrent pregnancy loss (RPL). These highly prevalent, distressing conditions have many unanswered questions regarding aetiology and management. Oestrogen receptor
Hannan Al-Lamee, Amy Ellison, Josephine Drury, Christopher J Hill, Andrew J Drakeley, Dharani K Hapangama, Nicola Tempest   +6 more
doaj   +1 more source

The RNA-seq based endometrial receptivity test (rsERT) compared to pinopode: A better diagnostic tool for endometrial receptivity for patients with recurrent implantation failure in Chinese population

Frontiers in Endocrinology, 2022
Displaced window of implantation (WOI) is one of the endometrial origins that accounts for implantation failure, especially for patients with recurrent implantation failure (RIF), yet no standard diagnostic tool has been recognized. The study consists of
Jingjing Chen, Jingjing Chen, Aihua He, Aihua He, Qiong Zhang, Qiong Zhang, Jing Zhao, Jing Zhao, Jing Fu, Jing Fu, Hui Li, Hui Li, Yanping Li, Yanping Li   +13 more
doaj   +1 more source

In search for an ideal marker of endometrial receptivity: from histology to comprehensive molecular genetics-based approaches

Alʹmanah Kliničeskoj Mediciny, 2019
Background: Despite significant improvements in the efficiency of assisted reproductive technologies (ART) for the past 10 years, proportion of unsuccessful cycles still remains significant and can reach up to 40%. Impairment of embryonic implantation is
M. V. Kibanov, G. M. Makhmudova, Ya. A. Gokhberg   +2 more
doaj   +1 more source

Histological endometrial dating: a reliable tool for personalized frozen-thawed embryo transfer in patients with repeated implantation failure in natural cycles

BMC Pregnancy and Childbirth, 2023
Objective To evaluate the clinical availability and stability of histological endometrial dating as a tool for personalized frozen-thawed embryo transfer (pFET) in patients with repeated implantation failure (RIF) in natural cycles.
Yuan Li, Quan Wen, Jing Hu, Jingnan Liao, Xiangxiu Fan, Huijun Chen, Qi Zhao, Guang-Xiu Lu, Ge Lin, Fei Gong   +9 more
doaj   +1 more source

Molecular control of the implantation window [PDF]

Human Reproduction Update, 1998
Human endometrium is the end organ of the hypothalamic-pituitary-ovarian axis. Therefore, endometrium is susceptible to changes in the cases of infertility that originate from disturbances in the normal functioning of this axis. In addition, some cases of unexplained infertility may be due to altered endometrial function.
openaire   +2 more sources

Autoimmune thyroid disease disrupts immune homeostasis in the endometrium of unexplained infertility women—a single-cell RNA transcriptome study during the implantation window

Frontiers in Endocrinology, 2023
ObjectiveAutoimmune thyroid disease (AITD) is known to be associated with unexplained infertility in women. Although the presence of antithyroid antibodies have been speculated to be a marker of an immune imbalance that might lead to implantation failure,
Jilai Xie, Aiyuan Gu, Huangyi He, Qiaohang Zhao, Ya Yu, Jian Chen, Zhangliang Cheng, Ping Zhou, Qi Zhou, Qi Zhou, Qi Zhou, Min Jin   +11 more
doaj   +1 more source