Results 51 to 60 of about 576,044 (343)

Personalized Medicine in Europe

Clinical and Translational Science, 2017
Personalised medicine is a promising new concept for dealing with challenges of health and health systems. With the launch of the International Consortium of Personalised Medicine, which brings together health research funders and policy making organisations, European countries aim to coordinate research and health policy to advance the implementation ...
Elmar Nimmesgern, Irene Norstedt, Indridi Benediktsson   +2 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Artificial Intelligence toward Personalized Medicine

Pharmaceutical Sciences and Research, 2021
In current medical practice when a patient feels symptoms he/she would consult the doctor. The doctor then gives medication in a one-fits-all fashion.
Muhammad Wildan Gifari, Pugud Samodro, Dhadhang Wahyu Kurniawan   +2 more
doaj   +1 more source

EPMA position paper in cancer:current overview and future perspectives [PDF]

, 2015
At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav, Danesi, Romano, Desiderio, Dominic M., Grech, Godfrey, Hagan, Suzanne, Vittadini, Giorgio, Yoo, Byong Chul, Zhan, Xianquan   +7 more
core   +5 more sources

Nanotheranostics for personalized medicine [PDF]

Expert Review of Molecular Diagnostics, 2013
Nanotheranostics, the integration of diagnostic and therapeutic function in one system using the benefits of nanotechnology, is extremely attractive for personalized medicine. Because treating cancer is not a one-size-fits-all scenario, it requires therapy to be adapted to the patient's specific biomolecules.
Xiaoyuan Chen, Seulki Lee, Tae Hyung Kim
openaire   +3 more sources

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Toward Personalized Medicine: Does Genetic Diagnosis of Pediatric Cardiomyopathy Influence Patient Management? [PDF]

, 2015
A goal of personalized medicine is to provide increasingly sophisticated, individualized approaches to management and therapy for disease. Genetics is the engine that drives personalized medicine, holding the promise of therapeutics directed toward the ...
Lee, Teresa M., Ware, Stephanie M.
core   +1 more source

Beyond Personalized Medicine [PDF]

Personalized Medicine, 2009
hope [1]. The aim of this article is to illustrate the path of pharmacogenomics through Seige’s cycle, from euphoria to disappointment. On this basis, I argue for the necessity of a more holistic view of individualized medicine without equating it to pharmacogenomics.
openaire   +4 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice

Frontiers in Microbiology, 2020
Altered composition of the gut microbiota has been observed in many neurodegenerative diseases. LanCL1 has been proven to protect neurons and reduce oxidative stress.
Fangxing Zhang, Fangxing Zhang, Fangxing Zhang, Nana Qi, Nana Qi, Nana Qi, Yanyu Zeng, Yanyu Zeng, Yanyu Zeng, Mengying Bao, Mengying Bao, Mengying Bao, Yang Chen, Yang Chen, Jinling Liao, Jinling Liao, Jinling Liao, Luyun Wei, Luyun Wei, Dehao Cao, Dehao Cao, Shengzhu Huang, Shengzhu Huang, Qianqian Luo, Qianqian Luo, Yonghua Jiang, Yonghua Jiang, Yonghua Jiang, Zengnan Mo, Zengnan Mo, Zengnan Mo   +30 more
doaj   +1 more source