Results 51 to 60 of about 4,097,121 (312)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Acknowledgement to Reviewers of Journal of Personalized Medicine in 2017

, 2018
Peer review is an essential part in the publication process, ensuring that Journal of Personalized Medicine maintains high quality standards for its published papers.[...
Journal of Personalized Medicine Editorial Office
core   +1 more source

Personalized Nursing and Health Care: Advancing Positive Patient Outcomes in Complex and Multilevel Care Environments [PDF]

, 2022
This Special Issue of the Journal of Personalised Medicine invited manuscripts that further establish the current state of science relating to personalized nursing and health care [...
David Edvardsson, Edvardsson David, Riitta Suhonen, Suhonen, Riitta, Minna Stolt, Edvardsson, David, Suhonen Riitta, Stolt, Minna, Stolt Minna   +8 more
core   +1 more source

Beyond Personalized Medicine [PDF]

Personalized Medicine, 2009
hope [1]. The aim of this article is to illustrate the path of pharmacogenomics through Seige’s cycle, from euphoria to disappointment. On this basis, I argue for the necessity of a more holistic view of individualized medicine without equating it to pharmacogenomics.
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Acknowledgement to Reviewers of Journal of Personalized Medicine in 2015

, 2016
The editors of Journal of Personalized Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
Journal of Personalized Medicine Editorial Office
core   +1 more source

The Endogenous Alterations of the Gut Microbiota and Feces Metabolites Alleviate Oxidative Damage in the Brain of LanCL1 Knockout Mice

Frontiers in Microbiology, 2020
Altered composition of the gut microbiota has been observed in many neurodegenerative diseases. LanCL1 has been proven to protect neurons and reduce oxidative stress.
Fangxing Zhang, Fangxing Zhang, Fangxing Zhang, Nana Qi, Nana Qi, Nana Qi, Yanyu Zeng, Yanyu Zeng, Yanyu Zeng, Mengying Bao, Mengying Bao, Mengying Bao, Yang Chen, Yang Chen, Jinling Liao, Jinling Liao, Jinling Liao, Luyun Wei, Luyun Wei, Dehao Cao, Dehao Cao, Shengzhu Huang, Shengzhu Huang, Qianqian Luo, Qianqian Luo, Yonghua Jiang, Yonghua Jiang, Yonghua Jiang, Zengnan Mo, Zengnan Mo, Zengnan Mo   +30 more
doaj   +1 more source

The forthcoming era of precision medicine [PDF]

Acta Medica Academica, 2016
. The aim of this essay is to present the definition and principles of personalized or precision medicine, the perspective and barriers to its development and clinical application.
Stjepan Gamulin
doaj   +1 more source

Personalized Medicine: A Personal View

Current Oncology, 2010
After the discovery of the breast cancer–associated genes BRCA1 in 1994 and BRCA2 in 1995, genetic testing was introduced into clinical practice in North America and Europe[...]
openaire   +2 more sources

Biobanks and personalized medicine [PDF]

Clinical Genetics, 2014
AbstractWe provide a mini‐review of how biobanks can support clinical genetics in the era of personalized medicine. We discuss types of biobanks, including disease specific and general biobanks not focused on one disease. We present considerations in setting up a biobank, including consenting and governance, biospecimens, risk factor and related data ...
J E, Olson, S J, Bielinski, E, Ryu, E M, Winkler, P Y, Takahashi, J, Pathak, J R, Cerhan   +6 more
openaire   +2 more sources