Results 131 to 140 of about 2,557,779 (357)

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Persona Journey Mapping to Drive Equity During an LMS Transition

open access: yesIssues and Trends in Learning Technologies
Technology systems that support learning–such as Learning Management Systems, or LMS’s–can change frequently in higher education. This often creates significant challenges for faculty-support staff during a transition–or migration–period.
Kam Moi Lee   +2 more
doaj   +2 more sources

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

Administración de Recursos Humanos : La Empresa y las Personas [PDF]

open access: yes, 2016
El presente trabajo cuyo tema general es la Administración de Recursos Humanos, está enmarcado en la empresa y las personas. El objetivo general es describir la relación entre la organización y las personas a través de una investigación documental para ...
Guido Téllez, Rosa Ivania   +1 more
core  

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

'Surviving the Wilds of Academia': Personas Depicting Early-Career Engineering Education Scholars Role Crafting to Achieve Their Goals

open access: yesStudies in Engineering Education
Background: The increase in doctoral programs and certifications in the area of engineering education has led to an increase in Engineering Education Scholars (EES) on the job market.
Cheryl A. Bodnar   +5 more
doaj   +1 more source

Aplicación móvil para auxilio de personas [PDF]

open access: yes, 2016
Este artículo describe el desarrollo de un software, en concreto de una aplicación móvil y una aplicación web que gestionan el envío de alertas con localización GPS del afectado en casos de emergencia.
García Colacios, Juan José   +1 more
core  

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