Results 121 to 130 of about 510,738 (303)

Theory of Mind: A Review of Recent Empirical Results and Main Theoretical Explanations

open access: yesPsychological Topics, 2023
Theory of Mind is the ability to attribute mental states to others. Until around 20 years ago most evidence pointed to Theory of Mind being a cognitively demanding skill that likely develops at around 4 years of age.
Edward W. Legg
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

ILR Impact Brief - Building Trust and Cooperation in Boundary-Spanning Teams [PDF]

open access: yes, 2008
[Excerpt] Knowledge workers engaged in interorganizational collaborative initiatives (i.e., boundary spanners) can actively build and maintain interpersonal trust through a multi-step “threat regulation” process.
Williams, Michele
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Impact of Empathy and Perspective-Taking on Medical Student Satisfaction and Performance: A Meta-Ethnography and Proposed Bow-Tie Model

open access: yesInternational Medical Education
Background: Empathy and perspective-taking are, respectively, associated with improved healthcare and educational outcomes. However, numerous studies show that medical students are experiencing a significant decline in self-reported empathy.
Chao Tian Tang   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Thermodynamics of rotating Bose gases in a trap

open access: yes, 2010
Novel ground state properties of rotating Bose gases have been intensively studied in the context of neutral cold atoms. We investigate the rotating Bose gas in a trap from a thermodynamic perspective, taking the charged ideal Bose gas in magnetic field (
Jaksch D   +4 more
core   +1 more source

Spatial perspective taking is distinct from cognitive and affective perspective taking.

open access: yesJournal of Experimental Psychology: General
Abstract Perspective taking (PT) is the ability to imagine viewpoints different from our own. However, the nature of PT as a construct, and its underlying cognitive mechanisms, are not well established. Some researchers propose that understanding what others believe (cognitive PT), feel (affective PT), and see (spatial PT) form a single
Maria Brucato   +2 more
openaire   +2 more sources

Perspective Taking and Advance Directives

open access: yesAMA Journal of Ethics, 2010
New brain imaging suggests that asking patients to put themselves in their surrogates’ shoes when thinking about advance directives might lead to directives that better line up with what surrogates think they should decide. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire   +2 more sources

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