Results 141 to 150 of about 5,838,612 (374)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Reduced spontaneous perspective taking in schizophrenia

open access: yesPsychiatry Research: Neuroimaging, 2019
Judgments about another person's visual perspective are impaired when the self-perspective is inconsistent with the other-perspective. This is a robust finding in healthy samples as well as in schizophrenia (SZ). Studies show evidence for the existence of a reverse effect, where an inconsistent other-perspective impairs the self-perspective.
Brandy Gale Pearce   +12 more
openaire   +4 more sources

The Social Perspective Taking Process: Strategies and Sources of Evidence in Taking Another’s Perspective [PDF]

open access: yes, 2013
Background/Context: Research indicates that social perspective taking – the capacity to discern the thoughts and feelings of others – plays a role in many important outcomes in schools.
Brinkworth, Maureen Elizabeth   +1 more
core  

Creativity through Connectedness: The Role of Closeness and Perspective Taking in Group Creativity

open access: yesCreativity Research Journal, 2018
Achievements in various fields of creativity are resulting more and more from collaborative teams. This research investigated the role of interpersonal process variables, namely closeness and perspective taking in group creativity, with a 2 by 2 ...
Pınar Oztop   +2 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Vicarious experiences and detection accuracy while observing pain and touch: the effect of perspective taking [PDF]

open access: yes, 2015
In this study, we investigated the effects of observing pain and touch in others on vicarious somatosensory experiences and the detection of subtle somatosensory stimuli.
Crombez, Geert   +3 more
core   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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