Results 41 to 50 of about 3,799,588 (281)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Painting American frontiers:"Encounter" and the borders of American identity in Nineteenth-Century art [PDF]

open access: yes, 2013
The historiographical perspective through which scholars see America, together with the persistent question of the particularity of America’s culture(s), have been developed and adapted in varied ways by recent scholars of the art of nineteenth-century ...
Peters Corbett, David   +1 more
core   +1 more source

A perspective on the ecological and evolutionary consequences of phenological variability in lake ice on north-temperate lakes

open access: yes, 2022
Climate change is leading to shifts in not only the average timing of phenological events, but also their variance and predictability. Increasing phenological variability creates a stochastic environment that is critically understudied, particularly in ...
Gerrish, Gretchen A   +4 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Measuring disease-specific quality of life in pediatric intestinal failure: Development and validation of the PIF-QoL

open access: yesIntestinal Failure
Background: Research suggests pediatric intestinal failure (PIF) patients experience impaired quality of life (QoL), but no disease-specific instrument has been available to assess this patient population.
Marie L. Neumann   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Switching memory perspective [PDF]

open access: yes, 2017
The perspective in which memories were spontaneously recalled, field (original perspective) or observer (see oneself in the memory), was examined for both recent and remote memories.
Justice, L.V.   +13 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Introducing time perspective coaching: A new approach to improve time management and enhance well-being [PDF]

open access: yesInternational Journal of Evidence Based Coaching and Mentoring, 2014
This article provides an overview of coaching methods and interventions that address different forms of imbalance in clients’ time perspectives, proposing a fresh look on dealing with multiple time management issues.
Ilona Boniwell   +2 more
doaj  

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