Results 61 to 70 of about 3,799,588 (281)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Call to Action Against Overweight and Obesity: Asia-Oceania Perspective
We the participants of the 6th Asia-Oceania Conference on Obesity,
Asia-Oceania Perspective
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Avons-nous encore besoin de héros nordiques ? [PDF]
L’art contemporain a joué un rôle essentiel dans la construction et la représentation des identités culturelles et de l’image nationale en Islande. S’appuyant sur un récit semi-fictionnel et généalogique de l’histoire de l’art, le rôle patriarcal de ...
Sigurjónsdóttir, Æsa
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Donor engagement in DRC is more important than ever – but donors need to reassess their strategies.
DRC: a donor perspective
doaj
Introduction To guide good practices in patient and public involvement (PPI), several calls have been made to share detailed accounts of practical experiences.
Femke vanSchelven +4 more
doaj +1 more source
IntroductionPublic speaking (PS) is a widespread activity required in many personal and professional settings. This activity is known to elicit anxiety, subsequently affecting oral communication, especially voice and speech parameters.
Lamia Bettahi +7 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
What is worth being measured in perspective taking? A psychometric perspective
What is worth being measured in perspective taking? A “true” mentalising process to study its universal functioning (cognitivist) Many forms and strategies of PT: Their form-specific and shared mechanisms Objective (unbiased) assessment (performance ...
Integrating current views on perspective taking +1 more
core

