Results 81 to 90 of about 281,401 (192)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

МЕТОДИЧЕСКИЙ ПОДХОД К ФОРМИРОВАНИЮ ОБЛИКА И ПОСТРОЕНИЮ БАЗ ДАННЫХ АВТОМАТИЗИРОВАННОЙ СИСТЕМЫ БЕЗОПАСНОГО СОПРОВОЖДЕНИЯ РЕАЛИЗАЦИИ НАЦИОНАЛЬНЫХ ИНТЕРЕСОВ

Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015
В процессе исследований было определено основные и специальные функции автоматизированной экспертно-аналитической системы (АЭАС), сформировано схему организации функции моделирования в АЭАС.
Volodymyr Y. Bohdanovych, Andrii L. Vysidalko   +1 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Stefan Bürger, Bruno Klein éd., en collaboration avec Katja Schröck, Werkmeister der Spätgotik : I, Position und Rolle der Architekten im Bauwesen des 14. bis 16. Jahrhunderts ; II, Personen, Amt und Image, Darmstadt, Wissenschaftliche Buchgesellschaft, 2009 et 2010

Perspective, 2013
Rédaction de Perspective
doaj   +1 more source

Underexplored Connections Between Diabetes, Hypomanic States and Insecure Attachment

Psychology Research and Behavior Management
Diana Bogdanova,1 Michael Maes,2– 8 Drozdstoj Stoyanov6– 8 1Clinical Psychologist at Center for Psychological Support – PSY HEALTH, Sofia, Bulgaria; 2Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, School of Medicine ...
Bogdanova D, Maes M, Stoyanov D
doaj  

Sociocultural issues in ESP written communication [PDF]

Diversitate si Identitate Culturala in Europa
Modern interdisciplinary approaches to communication have highlighted that this area stretches beyond the mastery and proficient use of vocabulary items or the separate study of culture.
Alina BUZARNA-TIHENEA (GĂLBEAZĂ)
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

An exploration of intercultural awareness and intercultural competence: Case Study [PDF]

Diversitate si Identitate Culturala in Europa
This paper is underlain by the stringent need to raise intercultural awareness and foster intercultural competence in contemporary environments increasingly marked by multiculturality.
Alina BUZARNA-TIHENEA (GALBEAZA)
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source