Results 51 to 60 of about 523,983 (302)
Sparse Gaussian Graphical Models with Discrete Optimization: Computational and Statistical Perspectives [PDF]
, 2023 Kayhan Behdin +2 more
openalex +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Integrative Systems Biology Visualization with MAYDAY
Journal of Integrative Bioinformatics, 2010 Visualization is pivotal for gaining insight in systems biology data. As the size and complexity of datasets and supplemental information increases, an efficient, integrated framework for general and specialized views is necessary.
Symonsy Stephan +3 more
doaj +1 more source
Schrift als Komponente der Bildschirmfläche am Beispiel der deutschen Nachrichtensendungen
Linguistik Online, 2020 The article focusses the written components of the screen surface in television news programs. The semiotic perspective represented in this article legitimises the viewpoint that they are not (ordinary) language signs. The main concern of this article is
Anna Kapuścińska
doaj +1 more source
A Corner-Highlighting Method for Ambient Occlusion
Applied Sciences, 2021 Graphical user experiences are now ubiquitous features, and therefore widespread. Specifically, the computer graphics field and the game industry have been continually favoring the ambient occlusion post-processing method for its superb indirect light ...
Sukjun Park, Nakhoon Baek
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Composing high-level stream processing pipelines
Journal of Big Data, 2020 The growing number of Internet of Things (IoT) devices provide a massive pool of sensing data. However, turning data into actionable insights is not a trivial task, especially in the context of IoT, where application development itself is complex.
Tanmaya Mahapatra
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Química NovaRelevant historical aspects concerning ideal gases were briefly reviewed to provide a condensed resource for the undergraduate student of chemistry. The importance of the barometer and the concept of atmospheric pressure were reviewed and discussed.
Leonardo M. Da Silva +1 more
doaj +1 more source