Results 61 to 70 of about 94,535 (296)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Effects of Stereoscopic 3D Contents on the Process of Learning to Build a Handmade PC

open access: yesKnowledge Management & E-Learning: An International Journal, 2011
We previously developed Web3D contents that simulate the procedure for assembling a handmade PC. The original motivation for this project was to enable media-informatics students to deepen their understanding of PC hardware.
Tosh Yamamoto   +4 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A comparative study of YOLOv5 and YOLOv8 for corrosion segmentation tasks in metal surfaces

open access: yesArray
This study delves into the comparative efficacy of YOLOv5 and YOLOv8 in corrosion segmentation tasks. We employed three unique datasets, comprising 4942, 5501, and 6136 images, aiming to thoroughly evaluate the models’ adaptability and robustness in ...
Edmundo Casas   +3 more
doaj   +1 more source

Composing high-level stream processing pipelines

open access: yesJournal of Big Data, 2020
The growing number of Internet of Things (IoT) devices provide a massive pool of sensing data. However, turning data into actionable insights is not a trivial task, especially in the context of IoT, where application development itself is complex.
Tanmaya Mahapatra
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Next-generation virtual consumer sensory and behaviour science: The evolving role of virtual reality eye-tracking—A graphical perspective

open access: yesActa Psychologica
Human–Food Interaction (HFI) research increasingly relies on precise sensory measurement. However, traditional methods often make it difficult to disentangle visual influences from multisensory integration and to reproduce context-rich eating-related ...
Abdul Hannan Bin Zulkarnain   +5 more
doaj   +1 more source

Utilisation de plans forestiers XVIIIe- XIXe siècles pour une étude archéologique des paysages passés de la forêt de Chailluz (Besançon) : l’exemple d’un réseau viaire

open access: yesBulletin du Centre d’Études Médiévales d’Auxerre, 2015
Today Besancon has the highest percentage of green space per inhabitant among France’s largest cities (200 m2 per capita). 3/4 of it are made up by the Forêt de Chailluz (16.7 km2), a large forest which has maintained its present extent for over six ...
Catherine Fruchart
doaj   +1 more source

Think Spatially With Game Engine

open access: yesISPRS International Journal of Geo-Information, 2020
Spatial thinking and spatial orientation skills are involved in tasks related to the recognition of landforms, mapping, spatial interpretation, and landscape analysis, and can be developed with specific training.
Carlos Carbonell-Carrera   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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