Results 71 to 80 of about 90,912 (255)
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
An IMS LD Graphic Editor using the graphs representation for modifying the course structures
Commentary on: Chapter 20: Delivery of Learning Design: the Explor@ System?s Case. (Paquette, Marino, De la Teja, Léonard, & Lundgren-Cayrol, 2005) Abstract: We developed a Web portal, named netUniversité, that enables the teachers to create their ...
Ecaterina Giacomini Pacurar +2 more
doaj +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
The convergence of quantum sensing and organ-on-a-chip (OoC) technologies represents an untapped frontier in biomedical diagnostics and personalised medicine.
Subham Preetam
doaj +1 more source
In this paper the nonlinear long-short (LS) wave resonance model is analyzed through a new perspective. We obtain the classification of exact solutions by making use of the complete discrimination system for the trial equation method and through the ...
Cimpoiasu Rodica, Pauna Alina Streche
doaj +1 more source
The interactions between two or more molecules or colloidal particles can be used to obtain a variety of self-assembled systems called supramolecules or supracolloids. There is a clear, but neglected, convergence between these two fields.
Loïc Leclercq
doaj +1 more source
Sum-Product Graphical Models: a Graphical Model Perspective on Sum-Product Networks [PDF]
The trade off between expressiveness of representation and tractability of inference is a key issue of probabilistic models. On the one hand, probabilistic Graphical Models (GMs) provide a high level representation of distributions, but exact inference with cyclic graphs is in general intractable.
openaire +2 more sources
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Low-Dimensional Materials for Future Transistors
The scaling of transistors is approaching its physical limits, making the future direction of transistor development a topic of global significance.
Shuohua Zhang +4 more
doaj +1 more source

