Results 121 to 130 of about 8,782,298 (371)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Social Perspective Taking Is Associated With Self-Reported Prosocial Behavior and Regional Cortical Thickness Across Adolescence

open access: yesDevelopmental Psychology, 2018
Basic perspective taking and mentalizing abilities develop in childhood, but recent studies indicate that the use of social perspective taking to guide decisions and actions has a prolonged development that continues throughout adolescence.
C. K. Tamnes   +6 more
semanticscholar   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Reducing Stigma toward the Transgender Community: An Evaluation of a Humanizing and Perspective-Taking Intervention [PDF]

open access: yes, 2014
Transgender (TG) individuals are an understudied group at high risk of experiencing discrimination and associated adverse mental health outcomes (IOM, 2011). Although many studies demonstrate that contact reduces negative attitudes toward out-groups, few
Hillman, Kimberly M.   +4 more
core   +1 more source

'Black Phones': postmodern poetics in the Holocaust poetry of Sylvia Plath [PDF]

open access: yes, 2008
This essay offers a fresh perspective on the Holocaust verse of the American poet Sylvia Plath, taking issue with the accusation that in her poetry she uses the Holocaust as a metaphor to figure her own personal pain.
Boswell, MJ
core   +2 more sources

Decoding the Charitable Brain: Empathy, Perspective Taking, and Attention Shifts Differentially Predict Altruistic Giving

open access: yesJournal of Neuroscience, 2016
Altruistic behavior varies considerably across people and decision contexts. The relevant computational and motivational mechanisms that underlie its heterogeneity, however, are poorly understood. Using a charitable giving task together with multivariate
A. Tusche   +4 more
semanticscholar   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

PISA 2022 insights on intellectual curiosity, perspective-taking, and science achievement: Examining the mediating pathways

open access: yesInternational Journal of Educational Research Open
The purpose of the study is to investigate the predictive roles of intellectual curiosity and perspective-taking on science achievement among Emirati early adolescents. Utilizing data from 24,600 participants of the 2022 Program for International Student
Othman Abu Khurma   +2 more
doaj   +1 more source

Standing in my customer's shoes: Effects of customer‐oriented perspective taking on proactive service performance

open access: yesJournal of Occupational and Organizational Psychology, 2018
We develop a theoretical framework that delineates the process by which customer-oriented perspective taking contributes to employees’ proactive service performance.
Y. Huo   +3 more
semanticscholar   +1 more source

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