Results 141 to 150 of about 8,782,298 (371)
Maintaining an ethical balance in the curriculum design of games-based degrees. [PDF]
In February 2011, games-based degrees were subjected to the scrutiny of the Livingstone- Hope report into the future of education in the fields of video games and visual effects.
Habgood, M. P. Jacob
core
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Group interviews with people taking long-term medication: comparing the perspectives of people with arthritis, respiratory disease and mental health problems [PDF]
Felicity Smith+2 more
openalex +1 more source
EEG correlates of egocentric and altercentric biases in forensic cases with borderline personality
People tend to consider others’ perspective when judging their own (altercentric interference, AI) or other (egocentric interference, EI) divergent views. Borderline (BDL) and antisocial personalities are associated with significant changes in EI and AI.
Vincent Rochas+10 more
doaj +1 more source
Contractualism and the Significance of Perspective-Taking [PDF]
Many of us think that perspective-taking is relevant to moral judgment. In this paper I claim that Scanlon’s contractualism provides an appealing and distinctive account of why this is so. Contractualism interprets our moral judgments as making claims about the reasons of individuals in various situations, reasons that we can only recognise by ...
openaire +3 more sources
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Qingqing Li,1– 3 Ming Gao,4 Yanfang Deng,4 Zongkui Zhou,1– 3 Jing Wang1– 3 1Key Laboratory of Adolescent Cyberpsychology and Behavior (CCNU), Ministry of Education, Wuhan, People’s Republic of China; 2Key Laboratory of Human Development and Mental Health
Li Q, Gao M, Deng Y, Zhou Z, Wang J
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Perspective Taking and Advance Directives
New brain imaging suggests that asking patients to put themselves in their surrogates’ shoes when thinking about advance directives might lead to directives that better line up with what surrogates think they should decide. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
openaire +3 more sources
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source