Results 81 to 90 of about 3,579,984 (327)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The effect of perspective taking on the mediation process

Psychology Research and Behavior Management, 2018
Stefano Boca, Maria Garro, Isabella Giammusso, Costanza Scaffidi Abbate Department of Psychology, University of Palermo, Palermo, Italy Background: Previous research demonstrated several benefits of strategic perspective taking in the field of intergroup
Boca S, Garro M, Giammusso I, Scaffidi Abbate C   +3 more
doaj  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Faktor Eksternal dari Orangtua atau Faktor Internal Diri Sendiri yang Memprediksi Emosi Moral Remaja?

Intuisi, 2020
Emosi moral memegang peran penting yang berfungsi sebagai motif munculnya kecenderungan tindakan moral dan mengantisipasi pelanggaran moral remaja, dan mampu memikirkan kesejahteraan orang lain.
Margaretha Maria Shinta Pratiwi, Subandi Subandi, Maria Goretti Adiyanti   +2 more
doaj   +1 more source

The Effects of Private Self-Consciousness and Perspective Taking on Satisfaction in Close Relationships. [PDF]

, 1985
131 heterosexual student couples, aged 17–32 yrs, 30 of whom were married or engaged answered questions concerning themselves and their relationships. It was predicted that individual differences in private self-consciousness would be positively related ...
Davis, Mark H., Franzoi, Stephen L., Young, Richard D.   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Perspective Taking Through Simulation

, 2005
Robots that operate among humans need to be able to attribute mental states in order to facilitate learning through imitation and collaboration. The success of the simulation theory approach for attributing mental states to another person relies on the ...
Demiris,Y.K.,, Johnson,M.R.,
core  

'Black Phones': postmodern poetics in the Holocaust poetry of Sylvia Plath [PDF]

, 2008
This essay offers a fresh perspective on the Holocaust verse of the American poet Sylvia Plath, taking issue with the accusation that in her poetry she uses the Holocaust as a metaphor to figure her own personal pain.
Boswell, MJ
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source