Enzymology of H2S Biogenesis, Decay and Signaling [PDF]
, 2013 Significance: Hydrogen sulfide (H2S), produced by the desulfuration of cysteine or homocysteine, functions as a signaling molecule in an array of physiological processes including regulation of vascular tone, the cellular stress response, apoptosis, and ...
Banerjee, Ruma, Kabil, Omer
core +1 more source
H2S biosynthesis and catabolism: new insights from molecular studies [PDF]
, 2017 Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO).
A Asimakopoulou +272 more
core +2 more sources
Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease [PDF]
, 2020 Hydrogen sulfide, a signaling molecule formed mainly from cysteine, is catabolized by sulfide:quinone oxidoreductase (gene SQOR). Toxic hydrogen sulfide exposure inhibits complex IV.
Banerjee, Ruma +20 more
core +3 more sources
Structural studies on enzymes involved in microbial hydrogen sulfide metabolism [PDF]
, 2021 "Hydrogen sulfide (H2S) is an ancient molecule present since Earth’s primordial atmosphere. Organisms from all Domains of Life early evolved to use this molecule in their physiologic activities.
Soares Costa, Sofia
core
Thiosulfate-cyanide sulfurtransferase a mitochondrial essential enzyme: from cell metabolism to the biotechnological applications [PDF]
, 2022 Thiosulfate: cyanide sulfurtransferase (TST), also named rhodanese, is an enzyme widely distributed in both prokaryotes and eukaryotes, where it plays a relevant role in mitochondrial function. TST enzyme is involved in several biochemical processes such
Arciero I., Buonvino S., Melino S.
core +1 more source
Regulation, sensory domains and roles of two Desulfovibrio desulfuricans ATCC27774 Crp family transcription factors, HcpR1 and HcpR2, in response to nitrosative stress [PDF]
, 2016 In silico analyses identified a Crp/Fnr family transcription factor (HcpR) in sulfate-reducing bacteria that controls expression of the hcp gene, which encodes the hybrid cluster protein and contributes to nitrosative stress responses.
Browning, D. +9 more
core +2 more sources
The Role of Bacillithiol in Gram-Positive Firmicutes [PDF]
, 2018 Significance: Since the discovery and structural characterization of bacillithiol (BSH), the biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent detoxification enzymes (FosB, Bst, GlxA/B) have been explored in Bacillus and ...
Antelmann, Haike +3 more
core +1 more source
Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily [PDF]
, 2016 Members of the Rrf2 superfamily of transcription factors are widespread in bacteria but their functions are largely unexplored. The few that have been characterized in detail sense nitric oxide (NsrR), iron limitation (RirA), cysteine availability (CymR)
AR Tesson +56 more
core +1 more source
Acidity and nucleophilic reactivity of glutathione persulfide [PDF]
, 2020 Persulfides (RSSH/RSS2) participate in sulfur trafficking and metabolic processes, and are proposed to mediate the signaling effects of hydrogen sulfide (H2S). Despite their growing relevance, their chemical properties are poorly understood.
Alvarez, Beatriz +10 more
core +2 more sources
Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide [PDF]
, 2014 © Jeffrey Green, Matthew D Rolfe, and Laura J Smith. Molecular oxygen (O2) and nitric oxide (NO) are diatomic gases that play major roles in infection.
Green, J., Rolfe, M.D., Smith, L.J.
core +1 more source