Results 31 to 40 of about 676 (100)

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century

Microbial Biotechnology, Volume 16, Issue 6, Page 1203-1231, June 2023., 2023
The reference genome of Bacillus subtilis was first sequenced and annotated 25 years ago. At that time, some 42% of the coding sequences could not be assigned a function. In the present annotated update, 15% of the CDS remain functionless. An important contribution of newly identitied functions has been attributed to nucleic acid modifying enzymes and ...
Erhard Bremer, Alexandra Calteau, Antoine Danchin, Colin Harwood, John D. Helmann, Claudine Médigue, Bernhard O. Palsson, Agnieszka Sekowska, David Vallenet, Abril Zuniga, Cristal Zuniga   +10 more
wiley   +1 more source

Stimulus-responsive proteins involved in multi-process regulation of storage substance accumulation during rice grain filling under elevated temperature

BMC Plant Biology, 2023
Background The intensified global warming during grain filling deteriorated rice quality, in particular increasing the frequency of chalky grains which markedly impact market value.
Yufei Zhao, Tongyang Yin, Xuan Ran, Wenzhe Liu, Yingying Shen, Hao Guo, Yuxuan Peng, Chen Zhang, Yanfeng Ding, She Tang   +9 more
doaj   +1 more source

H2O2, NO, and H2S networks during root development and signalling under physiological and challenging environments: Beneficial or toxic?

Plant, Cell &Environment, Volume 46, Issue 3, Page 688-717, March 2023., 2023
Abstract Hydrogen peroxide (H2O2) is a reactive oxygen species (ROS) and a key modulator of the development and architecture of the root system under physiological and adverse environmental conditions. Nitric oxide (NO) and hydrogen sulphide (H2S) also exert myriad functions on plant development and signalling. Accumulating pieces of evidence show that
Soumya Mukherjee, Francisco J. Corpas
wiley   +1 more source

HIF-1 Has a Central Role in Caenorhabditis elegans Organismal Response to Selenium

Frontiers in Genetics, 2020
Selenium is a trace element for most organisms; its deficiency and excess are detrimental. Selenium beneficial effects are mainly due to the role of the 21st genetically encoded amino acid selenocysteine (Sec).
Laura Romanelli-Credrez, Maria Doitsidou, Mark J. Alkema, Gustavo Salinas   +3 more
doaj   +1 more source

The mitochondrial coenzyme Q junction and complex III: biochemistry and pathophysiology

The FEBS Journal, Volume 289, Issue 22, Page 6936-6958, November 2022., 2022
Coenzyme Q (CoQ) is the electron‐carrying lipid in the mitochondrial electron transport system. In mammals, it is the electron acceptor for mitochondrial dehydrogenases involved in metabolic pathways ranging from ATP synthesis, amino acid, and fatty acid oxidation to nucleotide biosynthesis, methylation, and hydrogen sulfide detoxification.
Rishi Banerjee, Janne Purhonen, Jukka Kallijärvi   +2 more
wiley   +1 more source

Signaling by reactive molecules and antioxidants in legume nodules

New Phytologist, Volume 236, Issue 3, Page 815-832, November 2022., 2022
Summary Legume nodules are symbiotic structures formed as a result of the interaction with rhizobia. Nodules fix atmospheric nitrogen into ammonia that is assimilated by the plant and this process requires strict metabolic regulation and signaling. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are involved as signal molecules at all
Samuel Minguillón, Manuel A. Matamoros, Deqiang Duanmu, Manuel Becana   +3 more
wiley   +1 more source

Proteome adaptations in Ethe1-deficient mice indicate a role in lipid catabolism and cytoskeleton organization via post-translational protein modifications

Bioscience Reports, 2013
Hydrogen sulfide is a physiologically relevant signalling molecule. However, circulating levels of this highly biologically active substance have to be maintained within tightly controlled limits in order to avoid toxic side effects.
Carlo Viscomi, Tatjana M. Hildebrandt, Ivano Di Meo, Massimo Zeviani, Hans‑Peter Braun   +4 more
doaj   +1 more source

Human mitochondrial persulfide dioxygenase is potently and reversibly inhibited by nitric oxide

Biochimie
Hydrogen sulfide (H2S) regulates multiple human physiological processes, its reactivity and range of action being tightly controlled through regulation of H2S-synthesizing and -detoxifying enzymes. H2S detoxification is mainly achieved by a mitochondrial sulfide detoxifying pathway including persulfide dioxygenase (PDO).
Francesca Giordano, Diogo H.P. Silva, Elena Forte, Alessandro Giuffrè, João B. Vicente   +4 more
openaire   +2 more sources

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin, Chen Qian, Wenhao Li, Qihan Wang, Qifeng Sheng, Zheqing Chen, Wei Zhang, Wenming Li, Gaoran Ge, Zhanjun Yan, Dechun Geng   +10 more
wiley   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source