Results 11 to 20 of about 676 (100)

Protein polysulfidation-dependent persulfide dioxygenase activity of ethylmalonic encephalopathy protein 1 [PDF]

Biochemical and Biophysical Research Communications, 2016
Reactive persulfide species such as glutathione persulfide (GSSH) are highly abundant biomolecules. Persulfide dioxygenase (also called ethylmalonic encephalopathy protein 1, ETHE1) reportedly metabolizes GSSH to GSH with simultaneous oxygen consumption. How ETHE1 activity is regulated is still unclear, however.
Hisyam Abdul Hamid, Akira Nishimura, Shingo Kasamatsu   +2 more
exaly   +3 more sources

Mechanism of Intracellular Elemental Sulfur Oxidation in Beggiatoa leptomitoformis, Where Persulfide Dioxygenase Plays a Key Role. [PDF]

Int J Mol Sci
Representatives of the colorless sulfur bacteria of the genus Beggiatoa use reduced sulfur compounds in the processes of lithotrophic growth, which is accompanied by the storage of intracellular sulfur. However, it is still unknown how the transformation of intracellular sulfur occurs in Beggiatoa representatives.
Rudenko TS, Trubitsina LI, Terentyev VV, Trubitsin IV, Borshchevskiy VI, Tishchenko SV, Gabdulkhakov AG, Leontievsky AA, Grabovich MY.   +8 more
europepmc   +3 more sources

Causal links between iron status, mitochondrial function, and laryngeal and hypopharyngeal cancers: a Mendelian study [PDF]

Discover Oncology
Background This Mendelian randomization (MR) study aimed to investigate bidirectional causal relationships between genetically predicted iron homeostasis, mitochondrial function, and the risk of laryngeal and hypopharyngeal cancers. Methods Summary-level
Jiandong Zhao, Liwei Chen, Bing Han, Siyang Li, Yongxia Zhang, Ge Gao, Jinjing Liu   +6 more
doaj   +2 more sources

Ethylmalonic encephalopathy caused by biallelic truncating variants in ETHE1: A case report [PDF]

SAGE Open Medical Case Reports
Ethylmalonic encephalopathy is a rare autosomal recessive mitochondrial disorder caused by biallelic pathogenic variants in ETHE1 , the gene encoding mitochondrial persulfide dioxygenase, an enzyme crucial for hydrogen sulfide (H 2 S) detoxification ...
Delmer-Alejandro Ruiz-Martinez, Emilio-Rodrigo Vega-Peniche, Yazmin Quiñonez-Pacheco, Hugo Laviada-Molina, Carlos-Alejandro Medina-Campos, Felix-Julian Campos-Garcia   +5 more
doaj   +2 more sources

Transcriptome analysis reveals the mechanism and key role of CdPER47 in bermudagrass (Cynodon dactylon) adaptation to submergence and post-submergence stresses [PDF]

BMC Plant Biology
As an important turfgrass and forage grass, bermudagrass exhibits high tolerance to submergence stress, however, the molecular mechanisms are poorly clarified and required further elucidation.
Weitao Jia, Sihan Hou, Songyi Yang, Yuhan Zou, Wenqing Dou, Kai Zhu, Cunfeng Zhao, Shihui Zou, Huanhuan Liu, Lijiao Ai, Shengjun Wu   +10 more
doaj   +2 more sources

Rhodaneses minimize the accumulation of cellular sulfane sulfur to avoid disulfide stress during sulfide oxidation in bacteria

Redox Biology, 2022
Heterotrophic bacteria and human mitochondria often use sulfide: quinone oxidoreductase (SQR) and persulfide dioxygenase (PDO) to oxidize sulfide to sulfite and thiosulfate.
Mingxue Ran, Qingbin Li, Yufeng Xin, Shaohua Ma, Rui Zhao, Min Wang, Luying Xun, Yongzhen Xia   +7 more
doaj   +1 more source

Persulfide Biosynthesis Conserved Evolutionarily in All Organisms [PDF]

Antioxidants and Redox Signaling, 2023
Seiryo Ogata, Takaaki Akaike, Tetsuro Matsunaga   +2 more
exaly   +2 more sources

Characterizations of Two Bacterial Persulfide Dioxygenases of the Metallo-β-lactamase Superfamily [PDF]

Journal of Biological Chemistry, 2015
Persulfide dioxygenases (PDOs), also known as sulfur dioxygenases (SDOs), oxidize glutathione persulfide (GSSH) to sulfite and GSH. PDOs belong to the metallo-β-lactamase superfamily and play critical roles in animals, plants, and microorganisms, including sulfide detoxification.
Sattler, Steven A, Wang, Xia, Lewis, Kevin M, DeHan, Preston J, Park, Chung-Min, Xin, Yufeng, Liu, Honglei, Xian, Ming, Xun, Luying, Kang, ChulHee   +9 more
openaire   +3 more sources

Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis

Redox Biology, 2022
Regulation of H2S homeostasis in humans is poorly understood. Therefore, we assessed the importance of individual enzymes in synthesis and catabolism of H2S by studying patients with respective genetic defects.
Viktor Kožich, Bernd C Schwahn, Jitka Sokolová, Michaela Křížková, Tamas Ditroi, Jakub Krijt, Youssef Khalil, Tomáš Křížek, Tereza Vaculíková-Fantlová, Blanka Stibůrková, Philippa Mills, Peter Clayton, Kristýna Barvíková, Holger Blessing, Jolanta Sykut-Cegielska, Carlo Dionisi-Vici, Serena Gasperini, Ángeles García-Cazorla, Tobias B Haack, Tomáš Honzík, Pavel Ješina, Alice Kuster, Lucia Laugwitz, Diego Martinelli, Francesco Porta, René Santer, Guenter Schwarz, Peter Nagy   +27 more
doaj   +1 more source

The Response of Acinetobacter baumannii to Hydrogen Sulfide Reveals Two Independent Persulfide-Sensing Systems and a Connection to Biofilm Regulation

mBio, 2020
Acinetobacter baumannii is an opportunistic nosocomial pathogen that is the causative agent of several serious infections in humans, including pneumonia, sepsis, and wound and burn infections. A.
Brenna J. C. Walsh, Jiefei Wang, Katherine A. Edmonds, Lauren D. Palmer, Yixiang Zhang, Jonathan C. Trinidad, Eric P. Skaar, David P. Giedroc   +7 more
doaj   +1 more source