Results 41 to 50 of about 27,046 (149)
, 2016 Describing the organization of substrates and substrate analogues in the active site of cysteine dioxygenase identifies potential intermediates in this critical yet poorly understood reaction, the oxidation of cysteine to cysteine sulfinic acid.
Egor P. Tchesnokov (1893004) +5 more
core +1 more source
, 2015 Hydrogen sulfide (H2S) is both a lethal gas and an emerging gasotransmitter in humans, suggesting that the cellular H2S level must be tightly regulated. CstB is encoded by the cst operon of the major human pathogen Staphylococcus aureus and is under the ...
David P. Giedroc (1560214) +5 more
core +1 more source
, 2018 The sulfur dioxygenase ETHE1 oxidizes persulfides in the mitochondrial matrix and is involved in the degradation of L-cysteine and hydrogen sulfide. ETHE1 has an essential but as yet undefined function in early embryo development of Arabidopsis thaliana.
Christin Lorenz (5620052) +8 more
core +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Supersulfide biology and translational medicine for disease control
British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Cysteine Signalling in Plant Pathogen Response
Plant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann +6 more
wiley +1 more source
Evolution &Development, Volume 27, Issue 3, September 2025.Individuals of Asellus infernus, a sulfidic subterranean population of the Asellus aquaticus species complex from southeastern Romania (left) and surface individuals of A. aquaticus (right). Extreme differences in phenotype are seen comparing the subterranean and surface individuals as adults (top panels) and as embryonic samples (bottom panels ...
Haeli J. Lomheim +8 more
wiley +1 more source
Molecular Microbiology, Volume 124, Issue 3, Page 204-220, September 2025.In Hyphomicrobium denitrificans, the use of thiosulfate as a supplemental electron donor is regulated by two homologous sulfane‐sulfur responsive ArsR‐type transcriptional repressors, sHdrR and SoxR, that act cooperatively. Remarkably, the regulation by sHdrR/SoxR extends far beyond sulfur oxidation and deeply affects anaerobic metabolism, particularly
Jingjing Li +3 more
wiley +1 more source
Cancer Medicine, Volume 14, Issue 13, July 2025.ABSTRACT Background Mitochondria have been linked with inflammatory colorectal cancer (CRC) development; however, the association between mitochondria‐related genes (MRGs) and CRC remains unknown. Aims To explore the causal relationship between MRGs and CRC, screen prognostic genes, conduct drug prediction analyses, and investigate the correlations ...
Limin Zhu +4 more
wiley +1 more source