Results 41 to 50 of about 676 (100)

Cysteine Signalling in Plant Pathogen Response

Plant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.
ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann, Björn Heinemann, Cecile Angermann, Anna Koprivova, Ute Armbruster, Stanislav Kopriva, Tatjana M. Hildebrandt   +6 more
wiley   +1 more source

Comparative Embryology and Transcriptomics of Asellus infernus, an Isopod Crustacean From Sulfidic Groundwater

Evolution &Development, Volume 27, Issue 3, September 2025.
Individuals of Asellus infernus, a sulfidic subterranean population of the Asellus aquaticus species complex from southeastern Romania (left) and surface individuals of A. aquaticus (right). Extreme differences in phenotype are seen comparing the subterranean and surface individuals as adults (top panels) and as embryonic samples (bottom panels ...
Haeli J. Lomheim, Lizet Reyes Rodas, Devon Price, Serban M. Sarbu, Raluca I. Băncilă, Cody Carroll, Layla Freeborn, Sheri Sanders, Meredith E. Protas   +8 more
wiley   +1 more source

In Hyphomicrobium denitrificans Two Related Sulfane‐Sulfur Responsive Transcriptional Repressors Regulate Thiosulfate Oxidation and Have a Deep Impact on Nitrate Respiration and Anaerobic Biosyntheses

Molecular Microbiology, Volume 124, Issue 3, Page 204-220, September 2025.
In Hyphomicrobium denitrificans, the use of thiosulfate as a supplemental electron donor is regulated by two homologous sulfane‐sulfur responsive ArsR‐type transcriptional repressors, sHdrR and SoxR, that act cooperatively. Remarkably, the regulation by sHdrR/SoxR extends far beyond sulfur oxidation and deeply affects anaerobic metabolism, particularly
Jingjing Li, Nora E. Schmitte, Kaya Törkel, Christiane Dahl   +3 more
wiley   +1 more source

Self-S-sulfonation in a bacterial persulfide dioxygenase mediates thiol persulfide detoxification

A ubiquitous class of non-heme Fe(II) enzymes, the persulfide dioxygenases (PDOs), provide protection against hydrogen sulfide (H2S) poisoning. The PDO in humans is a single-domain enzyme, while bacterial PDOs, such as CstB of Staphylococcus aureus, are often fused to a sulfurtransferase (rhodanese) module.
Julius O. Campecino, Sofia S. Costa, Brenna J.C. Walsh, Jonathan C. Trinidad, Jyoti Kannoujia, Andrew T. Poor, Casey M. Van Stappen, Giovanni Gonzalez-Gutierrez, Margarida Archer, Jose A. Brito, David P. Giedroc   +10 more
openaire   +2 more sources

Mendelian Randomization Analysis of Mitochondria‐Related Genes and Screening of Prognostic Genes in Colorectal Cancer

Cancer Medicine, Volume 14, Issue 13, July 2025.
ABSTRACT Background Mitochondria have been linked with inflammatory colorectal cancer (CRC) development; however, the association between mitochondria‐related genes (MRGs) and CRC remains unknown. Aims To explore the causal relationship between MRGs and CRC, screen prognostic genes, conduct drug prediction analyses, and investigate the correlations ...
Limin Zhu, Xiaowei Huang, Fan Zhang, Jinzu Yang, Zhenye Xu   +4 more
wiley   +1 more source

Role of hydrogen sulfide in health and disease

MedComm, Volume 5, Issue 9, September 2024.
Abstract In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent years, with increased research, we have discovered that H2S can act as an endogenous regulatory transmitter. In mammals, H2S‐catalyzing enzymes, such as cystathionine‐β‐synthase, cystathionine‐γ‐lyase, and 3‐mercaptopyruvate sulfurtransferase, are ...
Yu‐Qing Jin, Hang Yuan, Ya‐Fang Liu, Yi‐Wen Zhu, Yan Wang, Xiao‐Yi Liang, Wei Gao, Zhi‐Guang Ren, Xin‐Ying Ji, Dong‐Dong Wu   +9 more
wiley   +1 more source

Distinct causal associations of mitochondrial function-related proteins with eclampsia versus pre-eclampsia: a two-sample Mendelian randomization analysis

The Journal of Maternal-Fetal & Neonatal Medicine
Objective Eclampsia (E) and pre-eclampsia (PE) exhibit significant pathophysiological differences, yet the mitochondrial mechanisms underlying these differences are unclear.
Zhuxiu Wang, Min Ma, Jiao Gu, Wei Lu, Tianyu Deng, Linqian Shi   +5 more
doaj   +1 more source

MarR family proteins sense sulfane sulfur in bacteria

mLife, Volume 3, Issue 2, Page 231-239, June 2024.
Abstract Members of the multiple antibiotic resistance regulator (MarR) protein family are ubiquitous in bacteria and play critical roles in regulating cellular metabolism and antibiotic resistance. MarR family proteins function as repressors, and their interactions with modulators induce the expression of controlled genes. The previously characterized
Guanhua Xuan, Luying Xun, Yongzhen Xia
wiley   +1 more source

Oxidation of Hydrogen Sulfide to Polysulfide and Thiosulfate by a Carbon Nanozyme: Therapeutic Implications with an Emphasis on Down Syndrome

Advanced Materials, Volume 36, Issue 10, March 7, 2024.
Oxidized carbon nanozymes catalytically oxidize hydrogen sulfide to polysulfides and thiosulfate in an oxygen‐dependent manner. In this report the reaction kinetics of polysulfide and thiosulfate formation both in a cell‐free setting and intracellularly and present the possible role of these nanozymes as a supportive therapy in Down Syndrome, a ...
Paul J. Derry, Anton V. Liopo, Karthik Mouli, Emily A. McHugh, Anh T. T. Vo, Ann McKelvey, Larry J. Suva, Gang Wu, Yan Gao, Kenneth R. Olson, James M. Tour, Thomas A. Kent   +11 more
wiley   +1 more source

Reactive oxygen species: Multidimensional regulators of plant adaptation to abiotic stress and development

Journal of Integrative Plant Biology, Volume 66, Issue 3, Page 330-367, March 2024.
This review provides an overview of recent advancements in reactive oxygen species detection methods, metabolism, signaling, and the significance of reactive oxygen species in plant growth, development, and adaptation to abiotic stress. ABSTRACT Reactive oxygen species (ROS) are produced as undesirable by‐products of metabolism in various cellular ...
Pengtao Wang, Wen‐Cheng Liu, Chao Han, Situ Wang, Ming‐Yi Bai, Chun‐Peng Song   +5 more
wiley   +1 more source