Results 41 to 50 of about 47,542 (262)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Approximate Conservation Laws of Nonvariational Differential Equations

open access: yesMathematics, 2019
The concept of an approximate multiplier (integrating factor) is introduced. Such multipliers are shown to give rise to approximate local conservation laws for differential equations that admit a small perturbation.
Sameerah Jamal
doaj   +1 more source

Perturbation theory for critical points of causal variational principles [PDF]

open access: yesAdvances in Theoretical and Mathematical Physics, 2020
The perturbation theory for critical points of causal variational principles is developed. We first analyze the class of perturbations obtained by multiplying the universal measure by a weight function and taking the push-forward under a diffeomorphism. Then the constructions are extended to convex combinations of such measures, leading to perturbation
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

New analytical solution for stream–aquifer interaction under constant replenishment

open access: yesApplied Water Science, 2018
In the present paper, approximate analytical solutions for flow in unconfined aquifers with streams are obtained assuming one-dimensional horizontal groundwater flow in homogeneous and isotropic aquifer with recharge effect using variational homotopy ...
Amruta Daga Bhandari   +2 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Size-dependent mechanics of viscoelastic carbon nanotubes: Modeling, theoretical and numerical analysis

open access: yesResults in Physics, 2020
This research presents the complex mechanics of the size-dependent viscoelastic carbon nanotube (CNT) subjected to the electric load. The mechanical model describing the motions of CNT is formulated by the Euler beam theory, Kelvin-Voigt viscoelastic ...
Mingyuan Li, Qiliang Wu, Bin Bai
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Numerical study of the applicability of the Saint-Venant principle

open access: yesMATEC Web of Conferences, 2017
The limits of the applicability of the Saint-Venant principle are investigated while using the LIRA-CAD app. A large number of bars loaded at the end with different loads are considered.
Paushkin Alexander, Saiyan Sergey
doaj   +1 more source

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