Results 51 to 60 of about 61,301 (268)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
g-FUNCTION IN PERTURBATION THEORY [PDF]
International Journal of Modern Physics A, 2004 We present some explicit computations checking a particular form of gradient formula for a boundary beta function in two-dimensional quantum field theory on a disk. The form of the potential function and metric that we consider were introduced in Refs. 16 and 18 in the context of background independent open string field theory.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Higher operations in perturbation theory
Journal of High Energy PhysicsWe discuss the role of formal deformation theory in quantum field theories and present various “higher operations” which control their deformations, (generalized) OPEs, and anomalies. Particular attention is paid to holomorphic-topological theories where
Davide Gaiotto +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Perturbation theory for traveling droplets [PDF]
Physical Review E, 2006 Motion of chemically driven droplets is analyzed by applying a solvability condition of perturbed hydrodynamic equations affected by the adsorbate concentration. Conditions for traveling bifurcation analogous to a similar transition in activator-inhibitor systems are obtained.
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Nonlinearized Perturbation Theories
Journal of Nonlinear Mathematical Physics, 1996 A brief review is presented of two recent perturbation algorithms. Their common idea lies in a not quite usual treatment of linear Schrödinger equations via nonlinear mathematical tools. The first approach (it is called a quasi-exact perturbation theory, QEPT) tries to get the very zero-order approximations already ``almost exact'', at a cost of ...
openaire +2 more sources
Implementing unitarity in perturbation theory [PDF]
Physical Review D, 2001 Unitarity cannot be perserved order by order in ordinary perturbation theory because the constraint $UU^\dagger=\1$ is nonlinear. However, the corresponding constraint for $K=\ln U$, being $K=-K^\dagger$, is linear so it can be maintained in every order in a perturbative expansion of $K$.
openaire +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source