Results 41 to 50 of about 6,274 (271)

Bifurcation of multi-bump homoclinics in systems with normal and slow variables

open access: yesElectronic Journal of Differential Equations, 2000
Bifurcation of multi-bump homoclinics is studied for a pair of ordinary differential equations with periodic perturbations when the first unperturbed equation has a manifold of homoclinic solutions and the second unperturbed equation is vanishing.
Michal Feckan
doaj  

Applications of the Kosambi–Cartan–Chern Theory to Hamiltonian Systems on a Cotangent Bundle: Linking Geometric Quantities to the Self-Similar Motions of Three Point Vortices

open access: yesMathematics
This study presents a differential geometric framework for Hamiltonian systems expressed in terms of first-order differential equations. For systems governed by second-order ordinary differential equations on tangent bundles, such as Euler–Lagrange ...
Yuma Hirakui, Takahiro Yajima
doaj   +1 more source

Stability of solutions for systems of delayed parabolic equations

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Background. The study is devoted to the analysis of stability in the sense Lyapunov steady state solutions for systems of linear parabolic equations with coefficients depending on time, and with delays depending on time.
Il'ya V. Boykov
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Reducing metastable continuous-space Markov chains to Markov chains on a finite set

open access: yes
We consider continuous-space, discrete-time Markov chains on $\mathbb{R}^d$, that admit a finite number $N$ of metastable states. Our main motivation for investigating these processes is to analyse random Poincar\'e maps, which describe random ...
Berglund, Nils
core   +2 more sources

Малые возмущения стохастических дифференциальных уравнений со степенными коэффициенами

open access: yes, 2016
Проблематика. Випадкові збурення звичайних диференціальних рівнянь розглядались у роботах Бафіко (1980), Бафіко, Балді (1982), Делару, Фландолі (2014), Делару, Фландолі, Вінченці (2014), Крикун, Махно (2013), Пилипенко, Проске (2015).
Приходько, Ю. Е.   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The stability of Cohen–Grossberg neural networks with time dependent delays

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Background. The study is devoted to the analysis of stability in the sense Lyapunov Cohen-Grossberg neural networks with time-dependent delays. To do this, we study the stability of the steady-state solutions of systems of linear differential equations ...
Il'ya V. Boykov   +2 more
doaj   +1 more source

Robust Controllability of Non-Stationary Differential-Algebraic Equations [PDF]

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2018
We consider linear time-varying system of first order ordinary differential equations with identically degenerate matrix of the derivative of the unknown function. Such systems are called differential-algebraic equations (DAE).
P.S. Petrenko
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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