Results 101 to 110 of about 124,541 (256)

Bordetella pertussisand Pertussis Vaccines [PDF]

Clinical Infectious Diseases, 2009
Bordetella pertussis is a human-specific pathogen that causes whooping cough. The use of pertussis whole-cell vaccines in infants and toddlers led to decreased circulation of the bacterium in the child population and a marked decrease in the incidence of the disease. However, vaccine does not result in life-long immunity; indeed, the circulation of the
openaire   +2 more sources

Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini, Riccardo Camilotto, Michele Maritan, Erika Morrone, Stephen Afriyie Boateng, Anna Vacilotto, Salvatore Pacifico, Remo Guerrini, Nurulain T. Zaveri, Girolamo Calo'   +9 more
wiley   +1 more source

Analysis of Bordetella pertussis pertactin and pertussis toxin types from Queensland, Australia, 1999–2003

BMC Infectious Diseases, 2006
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj   +1 more source

Understanding the High Incidence of Pertussis in Norway: The Role of Test Activity

Acta Paediatrica, EarlyView.
Margrethe Greve‐Isdahl, Elina Seppälä   +1 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Highlights of the 14th International Bordetella Symposium

mSphere
Pertussis, or whooping cough, is a highly contagious and acute respiratory illness caused primarily by the gram-negative coccobacillus Bordetella pertussis.
Kevin Munoz Navarrete, Kathryn M. Edwards, Kingston H. G. Mills, Jana Kamanová, María Eugenia Rodriguez, Andrew Gorringe, Andrew Preston, Beate Kampmann, Monica C. Gestal, Eric T. Harvill, Purnima Dubey, Dimitri A. Diavatopoulos, Seema Mattoo, Karen M. Scanlon, Camille Locht, Peter Sebo   +15 more
doaj   +1 more source

Genetically detoxified pertussis toxin induces superior antigen specific CD4 T cell responses compared to chemically detoxified pertussis toxin

Human Vaccines & Immunotherapeutics, 2019
Pertussis is resurgent worldwide. Currently available acellular pertussis vaccines contain chemically detoxified pertussis toxin (PTc); a highly immunogenic genetically detoxified pertussis toxin (PTg) vaccine has been off the market for over a decade ...
Naveen Surendran, Michael Pichichero
doaj   +1 more source

Perspectives on Pertussis Prevention

Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

The unheard ‘scandal’: Covid‐19 vaccine‐injured people's perceptions of the national redress scheme and trust in the government in the United Kingdom

Journal of Law and Society, EarlyView.
Abstract This article examines 218 Covid‐19 vaccine‐injured people's experiences of the process of seeking redress from the UK Government's Vaccine Damage Payment Scheme (VDPS). Moreover, it engages with the wider topic of how we can understand the government(s)’ role in dealing with an ‘emergency’ (the Covid‐19 pandemic) and the consequent (global ...
FANNI GYURKO, SONIA MACLEOD
wiley   +1 more source

Risk factors for pertussis among hospitalized children in a high HIV prevalence setting, South Africa

International Journal of Infectious Diseases, 2018
Background: In low- and middle-income countries, including South Africa, the epidemiology of pertussis in relation to immunization, nutritional, and HIV status is poorly described.
N.M. du Plessis, G. Ntshoe, G. Reubenson, R. Kularatne, L. Blumberg, J. Thomas, T. Avenant   +6 more
doaj   +1 more source