Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
The Dynamics of Real-Time Online Information and Disease Progression: Understanding Spatial Heterogeneity in the Relationship [PDF]
The re-emergence of infectious diseases such as measles and polio is creating logistics challenges for the state authorities to curb their spread and contain them.
Chen, Kuanchin +2 more
core +1 more source
Validation and implementation of a diagnostic algorithm for DNA Detection of Bordetella pertussis, B. parapertussis, and B-holmesii in a Pediatric Referral Hospital in Barcelona, Spain [PDF]
This study aimed to validate a comprehensive diagnostic protocolbased on real-time PCR for the rapid detection and identification ofBordetella per-tussis,Bordetella parapertussis, andBordetella holmesii, as well as its implementationin the diagnostic ...
Acosta Argueta, Lesly María +5 more
core +2 more sources
This single‐center retrospective study of pediatric solid organ transplant recipients found that vaccine‐specific serologies were rarely utilized to guide post‐transplant vaccination practices. Additionally, older age at the time of transplant, private insurance, and heart transplantation were identified as risk factors for delayed and incomplete non ...
Adam Z. Blatt +3 more
wiley +1 more source
Enhanced Bordetella pertussisacquisition rate in adolescents during the 2012 epidemic in the Netherlands and evidence for prolonged antibody persistence after infection. [PDF]
IntroductionIn 2012 a large epidemic of pertussis occurred in the Netherlands. We assessed pertussis toxin (PT) antibody levels in longitudinal serum samples from Dutch 10-18 year-olds, encompassing the epidemic, to investigate pertussis infection ...
Berbers, Guy A M +7 more
core +2 more sources
ABSTRACT Torque teno virus (TTV) is a ubiquitous, nonenveloped DNA virus of the Anelloviridae family and a proposed surrogate marker of immune competence. Although nonpathogenic, its replication reflects host immune status and is associated with immune dysregulation during respiratory viral infections (RVIs).
Roberto Ferrarese +13 more
wiley +1 more source
Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]
The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu +43 more
core +5 more sources
Do Childhood Vaccines Have Non-Specific Effects on Mortality [PDF]
A recent article by Kristensen et al. suggested that measles vaccine and bacille Calmette–Guérin (BCG) vaccine might\ud reduce mortality beyond what is expected simply from protection against measles and tuberculosis.
Boyce , G. Thomas +3 more
core
The Effect of Physical Disability on Employment
ABSTRACT The relationship between physical disability and employment is explored using microdata for older working‐age women in the 2016 Irish Census of Population and historical data on the incidence of infectious diseases. Two‐stage least squares and recursive bivariate probit estimations are employed to account for the potential endogeneity of ...
Irene Mosca
wiley +1 more source
Status and potential of bacterial genomics for public health practice : a scoping review [PDF]
Background: Next-generation sequencing (NGS) is increasingly being translated into routine public health practice, affecting the surveillance and control of many pathogens.
Boon, Nele AM +6 more
core +2 more sources

