Results 11 to 20 of about 9,259 (182)

Experiência de famílias e terapeutas com um programa de telessaúde para crianças e adolescentes com paralisia cerebral durante a pandemia de COVID-19. [PDF]

Dev Med Child Neurol
Experiências de pais de crianças com paralisia cerebral e terapeutas no programa individualizado. Resumo Objetivo Compreender as percepções das famílias e terapeutas sobre a sua participação em um programa domiciliar individualizado via telessaúde implementado para crianças e adolescentes com paralisia cerebral (PC) durante a pandemia da COVID‐19 no ...
Oliveira R, Mancini M, Figueiredo P, Bueno K, Gordon AM, Brandão M.   +5 more
europepmc   +2 more sources

Kynurenine pathway metabolite alterations in Down syndrome and Alzheimer's disease. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Down syndrome (DS) is a genetic disorder that leads to intellectual disability and accelerated aging, increasing the risk of Alzheimer's disease (AD). The pathophysiology of AD and DS is multifactorial, involving amyloid precursor protein overexpression, neuroinflammation, and oxidative stress.
Dos Reis RG, Singulani MP, Forlenza OV, Gattaz WF, Talib LL.   +4 more
europepmc   +2 more sources

Urine-Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome. [PDF]

J Neurochem
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Martins M, Nugue G, Aguiar A, Souza LRQ, Abrantes PV, Trajano JR, Stelling M, Junqueira M, Rehen S, Guimarães MZP.   +9 more
europepmc   +2 more sources

Reflections on research ethics in a public health emergency: Experiences of Brazilian women affected by Zika

Developing World Bioethics, Volume 23, Issue 2, Page 138-146, June 2023., 2023
Abstract In Brazil, the epicenter of the Zika crisis, brown, black, and indigenous poor women living in municipalities with scarce resources were disproportionally affected. The gendered consequences of the epidemic exposed how intersectional lenses are central to understand the impact of public health emergencies in the lives of women and girls.
Ilana Ambrogi, Luciana Brito, Sergio Rego   +2 more
wiley   +1 more source

Justifying (Non)Discrimination Against Disabled Workers in Emerging Economies: Managerial Choice, Business Versus Moral Case Arguments and Home Versus Host Country Effects

British Journal of Management, Volume 34, Issue 2, Page 767-786, April 2023., 2023
Abstract It is widely known that disabled people face discrimination in all walks of life, including employment. Unfortunately, legal protection often does not work as well as hoped, especially in emerging markets. This leads to the core objective of this study: to understand why firms might not discriminate against disabled people.
Pauline Dibben, Geoffrey Wood, Gareth Crockett, Nikola Bakalov   +3 more
wiley   +1 more source

Is the search for cerebral palsy ‘cures’ a reasonable and appropriate goal in the 2020s?

Developmental Medicine &Child Neurology, Volume 64, Issue 1, Page 49-55, January 2022., 2022
In the field of disability research and advocacy, the notion of ‘cures’ is contentious. Cerebral palsy (CP) is no exception. In this narrative review, we combine perspectives gained during community consultation undertaken for the Australian and New Zealand Cerebral Palsy Strategy, 2020 with those published in the scientific and grey literature to ...
Ingrid Honan, Megan Finch‐Edmondson, Christine Imms, Iona Novak, Amy Hogan, Shannon Clough, Bruce Bonyhady, Sarah McIntyre, Catherine Elliott, Shirley Wong, Michael Bink, Nadia Badawi   +11 more
wiley   +1 more source

Process evaluation of the Disability Allowance programme in the Maldives

International Social Security Review, Volume 75, Issue 1, Page 79-105, January/March 2022., 2022
Abstract Limited evidence on the design and implementation of social protection programmes for people with disabilities in low‐ and middle‐income countries constrains understanding of how their impacts could be improved. The Disability Allowance programme in the Maldives is a non means‐tested, monthly cash transfer targeting people with disabilities ...
Shaffa Hameed, Matthew Walsham, Lena Morgon Banks, Hannah Kuper   +3 more
wiley   +1 more source

Development of the Fearless, Tearless Transition model of care for adolescents with an intellectual disability and/or autism spectrum disorder with mental health comorbidities

Developmental Medicine &Child Neurology, Volume 63, Issue 5, Page 560-565, May 2021., 2021
Aim First, to understand the barriers to achieving effective transition and the supports required from the perspective of parents and carers, adolescents with intellectual disability and/or autism spectrum disorder and co‐existing mental health disorders (often termed ‘dual disability’), and those who provide services to this group.
Evelyn Culnane, Hayley Loftus, Daryl Efron, Katrina Williams, Nikki Di Iorio, Rebecca Shepherd, Catherine Marraffa, Lionel Lubitz, Giuliana Antolovich, Chidambaram Prakash   +9 more
wiley   +1 more source

School outcomes of adolescents with cerebral palsy in Sweden

Developmental Medicine &Child Neurology, Volume 63, Issue 4, Page 429-435, April 2021., 2021
Aim To study school outcomes of adolescents with cerebral palsy (CP) compared with a matched comparison group from the general population, and to observe to what extent sociodemographic and disability‐specific factors are associated with school outcomes.
Johan Jarl, Ann Alriksson‐Schmidt
wiley   +1 more source

The impact of the Lesotho Child Grant Programme in the lives of children and adults with disabilities: Disaggregated analysis of a community randomized controlled trial

International Social Security Review, Volume 74, Issue 2, Page 55-81, April/June 2021., 2021
Abstract Globally, people with disabilities are disproportionally affected by poverty. Social protection policies, including cash transfers, are key strategies to address poverty “in all its forms”, but it is currently unclear how such programmes affect people with disabilities.
Richard de Groot, Tia Palermo, Lena Morgon Banks, Hannah Kuper   +3 more
wiley   +1 more source