Efficient generation of recombinant RNA viruses using targeted recombination-mediated mutagenesis of bacterial artificial chromosomes containing full-length cDNA [PDF]
, 2013 BACKGROUND: Infectious cDNA clones are a prerequisite for directed genetic manipulation of RNA viruses. Here, a strategy to facilitate manipulation and rescue of classical swine fever viruses (CSFVs) from full-length cDNAs present within bacterial ...
Beer, Martin +7 more
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Recent Advances in Pestivirus Research
Journal of General Virology, 1989 Introduction. The term ‘pestivirus’ was coined in 1973 to group together two antigenically related enveloped RNA viruses: hog cholera virus (HCV) and bovine viral diarrhoea virus (BVDV; Horzinek, 1973). A third animal pathogen, the border disease virus (BDV) of sheep, was found later to be a close relative of BVDV.
Horzinek, M.C. +2 more
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Detection of Pestivirus in small ruminants in Central Java, Indonesia [PDF]
Veterinary World, 2021 Background and Aim: Globally, pestiviruses are among the most economically important viral pathogens of livestock. The genus Pestivirus comprises four species, including bovine viral diarrhea virus type 1 and 2 (BVDV-1 and BVDV-2), which infect cattle ...
W. Hidayat, H. Wuryastuty, R. Wasito
doaj +1 more source
Distribution of Pestivirus exposure in wild ruminants in Spain
Transboundary and Emerging Diseases, 2020 A large-scale study was carried out to determine the prevalence of antibodies against Pestivirus species in wild ruminants and describe their spatial variation in mainland Spain. Serum samples of 1,874 wild ruminants from different regions of this country were collected between the years 2000 and 2017.
Félix Gómez-Guillamón +16 more
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Genomic characteristics of classical swine fever virus strains of bovine origin according to primary and secondary sequence structure analysis [PDF]
Open Veterinary Journal, 2020 Background: Classical swine fever virus (CSFV), species member of the family Flaviviridae, is generally considered restricted to domestic and wild suids. Circulation of CFSV has been detected in cattle herds in China and India. Natural infection appeared
Massimo Giangaspero, Shu-Qin Zhang
doaj +1 more source
Protocol for a Scoping/Systematic Review: Scoping Review of Vaccination for the Prevention of Calf Scours in Cow-Calf Operations [PDF]
, 2020 Background: The use of antimicrobials in the livestock industry has been a topic of increasing concern in the last few years. Calf scours is one of the main causes of mortality among calves younger than 1 month and affects the development of the animal,
Breitenbuecher, Jefferson GC +4 more
core
Mechanism of action of a pestivirus antiviral compound [PDF]
Proceedings of the National Academy of Sciences, 2000 We report here the discovery of a small molecule inhibitor of pestivirus replication. The compound, designated VP32947, inhibits the replication of bovine viral diarrhea virus (BVDV) in cell culture at a 50% inhibitory concentration of approximately 20 nM.
Siu Chi Chang Sun +7 more
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Journal of General Virology, 2004 The genus Pestivirus within the family Flaviviridae currently consists of four different main species: Classical swine fever virus, Bovine viral diarrhea virus types 1 and 2 and Border disease virus. A fifth tentative species is represented by an isolate from a giraffe.
Martin Beer +4 more
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Seroprevalences of Newly Discovered Porcine Pestiviruses in German Pig Farms
Veterinary Sciences, 2019 Several novel porcine pestiviruses that are linked to disease outbreaks in commercial pig farms were discovered during recent years. Bungowannah pestivirus (BuPV; new species Pestivirus F) causes sudden death in young pigs, but has only ever been ...
Anna Michelitsch +4 more
doaj +1 more source
Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]
, 2015 Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A +6 more
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