Results 221 to 230 of about 76,229 (261)
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Copper and Gallium PET Imaging Agents for Applications in HIV and Cancer

2021
Positron emission tomography (PET) is a sensitive nuclear imaging technique that can highlight physiological and biochemical processes in vivo. If we extend the current utility of PET, we can both diagnose disease earlier, and improve our understanding of disease evolution. This thesis represents an investigation into PET applications in HIV and cancer,
openaire   +2 more sources

Site-specific 68Ga-labeled Annexin A5 as a PET imaging agent for apoptosis

Nuclear Medicine and Biology, 2011
Two variants of Annexin A5 (Cys2-AnxA5 and Cys165-AnxA5) were labelled with Gallium-68 in order to evaluate their biological properties.Biodistribution and pharmacokinetics of the radiotracers were studied with μPET in healthy mice and in a mouse model of hepatic apoptosis.
Bauwens, Matthias   +8 more
openaire   +2 more sources

The development and evaluation of PET imaging agents targeting PD-L1

2023
The Programmed Cell Death Protein-1/ Ligand 1 (PD-1/ PD-L1) axis and its inhibitors have transformed cancer therapy. PD-L1 targeting immune checkpoint inhibitors (ICPIs) contribute to the reinvigoration of exhausted T cells in the cancer immune response.
openaire   +1 more source

Molecular imaging in oncology: Current impact and future directions

Ca-A Cancer Journal for Clinicians, 2022
Martin Pomper, Steven Rowe
exaly  

WITHDRAWN:New PET imaging agents in the management of solid cancers.

Current opinion in oncology
Ahead of Print article withdrawn by publisher.
Camilo, Garcia   +2 more
openaire   +1 more source

Phosphoramidate-based Peptidomimetic Prostate Cancer PET Imaging Agents

2013
Abstract : The main goal is to develop a PET imaging agent based on modifying the peptidomimetic PSMA inhibitor which will result in improved tumor uptake and clearance mechanism. Different fluorination approaches were attempted with PSMA module compounds such as direct labeling, cupper free chemistry and the use of prosthetic group (SFB).
openaire   +1 more source

Research progress of 18F labeled small molecule positron emission tomography (PET) imaging agents

European Journal of Medicinal Chemistry, 2020
Mingliang Zhang   +2 more
exaly  

Multimodality Imaging Agents with PET as the Fundamental Pillar

Angewandte Chemie - International Edition, 2019
Dalong Ni, Emily Ehlerding, Weibo Cai
exaly  

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