Results 181 to 190 of about 756,186 (307)

Application of [¹⁸F]NaF and [¹⁸F]FDG PET/CT to Assess Molecular Calcification and Glucose Metabolism in Thyroid Cartilage. [PDF]

Cartilage
Motamedi N, Singh SB, Ismoilov M, Niazi SK, Shrestha BB, Ahmed M, Gandhi OH, Werner TJ, Torigian DA, Alavi A, Revheim ME.   +10 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Renal Medullary Carcinoma: Utility of [¹⁸F]FDG PET/CT in Evaluating Extent of Disease and Impact on Treatment Management. [PDF]

J Nucl Med
Krebs S, Salem AE, Nguyen NC, Sheth RA, Karam JA, Daw NC, Tang C, Tannir NM, Msaouel P, Surasi DS.   +9 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

68Ga-FAPI-04 PET/CT has high diagnostic efficacy in Tg-positive and Tg-negative differentiated thyroid cancer. [PDF]

PLoS One
Mou L, Zhang T, Zhang X, Zhou J, Chen Y, Wang W.   +5 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Functional Renal Assessment via Dynamic LAFOV ¹⁸F-FDG PET/CT in a Patient with Recurrent Extranodal Marginal-Zone Lymphoma. [PDF]

J Nucl Med
Kuten J, Beattie BJ, Chahwan S, Schöder H.   +3 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Imaging Modality and Outcomes of Metastasis-Directed Therapy in Oligometastatic Castration-Resistant Prostate Cancer: An Updated Analysis of the PRECISE-MDT Cohort. [PDF]

J Nucl Med
Bauckneht M, Belgioia L, Albano D, Triggiani L, Linguanti F, Urso L, Mazzola R, Rizzo A, D'Angelo E, Dondi F, Mataj E, Pedersoli G, Abenavoli EM, Vaggelli L, Detti B, Ortolan N, Malorgio A, Guarneri A, Garrou F, Passoni J, Fiorini M, Grimaldi S, Ghedini P, Iorio GC, Iudicello A, Rovera G, Fornarini G, Zanardi E, Bongiovanni D, Marcenaro M, Agosti A, Timon G, Salgarello M, Racca M, Bartolomei M, Panareo S, Ricardi U, Bertagna F, Alongi F, Barra S, Morbelli S, Lanfranchi F, Sambuceti G.   +42 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source