Results 51 to 60 of about 570,057 (299)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Characterization of PET image using global and local entropy

open access: yesBrazilian Journal of Radiation Sciences, 2015
In the clinical practice PET imaging provides semi-quantitative information about metabolic activities in human body, using the Standardized Uptake Value (SUV).
Igor Fagner Vieira
doaj   +1 more source

PET-CT and Occupational Exposure in Oncological Patients

open access: yesSciMedicine Journal, 2020
The paper describes the results of retrospective epidemiological study on low dose effects of diagnostic radiation exposure to humans. The data used in the study has been collected from archives of Chelyabinsk Regional Clinical Center of Oncology and ...
Mikhail Osipov   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Rapid cleavage of 6-[18F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Peptides radiolabeled with fluorine-18 are frequently synthesized using prosthetic groups. Among them, activated esters of 6-[18F]fluoronicotinic acid ([18F]FNA) have been prepared and successfully employed for 18F-labeling of diverse ...
Pyry Dillemuth   +15 more
doaj   +1 more source

Antalya'nın Termal Konfor Özellikleri, İklim Model Verileri Kullanılarak Gelecek Projeksiyonları ve Turizme Etkileri

open access: yesCoğrafi Bilimler Dergisi, 2020
Climate data has a crucial role for planning and mitigation activities in the tourism. Trends in the Physiologically Equivalent Temperatures (FES) will provide important information to tourism.
Serhat Şensoy   +3 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Physiological myocardial 18F-FDG uptake pattern in oncologic PET/CT: comparison with findings in cardiac sarcoidosis [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology
Objective(s): Physiological myocardial 18F-fluorodeoxyglucose (18F-FDG) uptake in oncologic positron emission tomography (PET)/computed tomography (CT) is commonly observed with multiple variations under clinical fasting conditions.
Takashi Norikane   +7 more
doaj   +1 more source

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