Results 71 to 80 of about 1,691,728 (255)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Perceptions among university students in Seville (Spain) of the rabbit as livestock and as a companion animal

World Rabbit Science, 2012
The rabbit has various utilities and roles, mainly as a meat-producing animal, game species, companion animal, laboratory animal or pest. Among these roles, rabbit breeding for meat has traditionally prevailed in the Mediterranean countries.
Pedro González-Redondo, Gema M. Contreras-Chacón   +1 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Hospitality on a Leash: A Study of the Online Visibility, Availability and Distribution of Pet-friendly Accommodations in Romania

Studia Universitatis Babeş-Bolyai: Geographia
Hospitality on a Leash: a Study of the Online Visibility, Availability and Distribution of Pet-Friendly Accommodations in Romania. The present paper explores the growing phenomenon of pet travel within contemporary tourism, focusing on the preferences ...
Gabriela MUNTEANU
doaj   +1 more source

Children\u27s experiences of companion animal maltreatment in households characterized by intimate partner violence [PDF]

, 2015
Cruelty toward companion animals is a well-documented, coercive tactic used by abusive partners to intimidate and control their intimate partners. Experiences of co-occurring violence are common for children living in families with intimate partner ...
Adamson, Arkow, Ascione, Ascione, Ascione, Ascione, Atlas.ti Scientific Software Development, Bancroft, Berger, Boyatzis, Carlson, Crabtree, Cunningham, Davies, DeGue, DeGue, Dockett, Edleson, Edleson, Edleson, Elizabeth A. Collins, Evang, Faver, Faver, Faver, Felthous, Finkelhor, Finkelhor, Flynn, Flynn, Flynn, Fosco, Frank R. Ascione, Giorgi, Glaser, Hackett, Hamby, Jaffe, James Herbert Williams, Joseph, Katcher, Katcher, Khan, King, King, Knickerbocker, Kosonen, Lee, Long, Lynch, Margolin, Margolin, Mayoh, McCabe, McDonald, McGee, Melson, Melson, Millikin, Nicole Nicotera, Onyskiw, Petersen, Renner, Sandra A. Graham-Bermann, Shelby Elaine McDonald, Simmons, Solberg, Spratling, Strauss, Tajima, Tallichet, Tina O. Hageman, Travis, Van de Vijver, Volant, Warrens, Yorke, Överlien   +77 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Rapid cleavage of 6-[18F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules

EJNMMI Radiopharmacy and Chemistry
Background Peptides radiolabeled with fluorine-18 are frequently synthesized using prosthetic groups. Among them, activated esters of 6-[18F]fluoronicotinic acid ([18F]FNA) have been prepared and successfully employed for 18F-labeling of diverse ...
Pyry Dillemuth, Abiodun Ayo, Xiaoqing Zhuang, Petter Lövdahl, Heidi Liljenbäck, Salli Kärnä, Tatsiana Auchynnikava, Jonne Kunnas, Jesse Ponkamo, Maxwell W. G. Miner, Johan Rajander, Jessica M. Rosenholm, Anne Roivainen, Anu J. Airaksinen, Pirjo Laakkonen, Xiang-Guo Li   +15 more
doaj   +1 more source

Synthesis of Positron Emission Tomography (PET) Images via Multi-channel Generative Adversarial Networks (GANs)

, 2017
Positron emission tomography (PET) image synthesis plays an important role, which can be used to boost the training data for computer aided diagnosis systems.
A Esteva, A Gholipour, CK Hoh, EU Mumcuoglu, H Chen, H Li, K Doi, K Kamnitsas, L Bi, L Bi, N Burgos, O Ronneberger, T Kooi, U Nestle, V Gulshan, Y Song   +15 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A New Positron Emission Tomography Probe for Orexin Receptors Neuroimaging

Molecules, 2020
The orexin receptor (OX) is critically involved in motivation and sleep−wake regulation and holds promising therapeutic potential in various mood disorders. To further investigate the role of orexin receptors (OXRs) in the living human brain and to
Ping Bai, Sha Bai, Michael S. Placzek, Xiaoxia Lu, Stephanie A. Fiedler, Brenda Ntaganda, Hsiao-Ying Wey, Changning Wang   +7 more
doaj   +1 more source