Results 91 to 100 of about 1,691,728 (255)
Radiology and Oncology, 2020 According to the current pathological classification, lung adenocarcinoma includes histological subtypes with significantly different prognoses, which may require specific surgical approaches.
Carretta Angelo +9 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fabricación de ladrillos a base de polímeros PET y virutas metálicas
Revista de Iniciación Científica, 2018 En este artículo se plantea la fabricación de ladrillos de plástico fundido con virutas producto del mecanizado como un elemento constructivo. En este trabajo el material utilizado es el polietileno de tereftalato, mejor conocido como PET.
José Luis Maure +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Laboratory Studies on the Production of Asphalt Mixture Bad 22,4 with Pet (Plastic Bottle Fibers)
Romanian Journal of Transport InfrastructurePlastic is a versatile and cheap material, but extremely durable and nearly impossible to decompose in nature. Plastic waste is not only a visual pollution issue but also a global health problem, as microplastics enter the food chain, affecting both ...
Claudiu-Ionel Chicuș +3 more
doaj +1 more source
The Research Progress of Monoclonal Antibody Labeled with 89Zr
Journal of IsotopesZirconium-89 (89Zr) is a metallic positron-emitting radionuclide. The relatively long half-life and moderate energy making 89Zr especially suitable for the labeling of large biomolecules such as antibodies for radioimmuno-PET (positron emission ...
Zhanxiong XIAO, Fei DUAN, Hongyu LI
doaj +1 more source
A novel TOF-PET MRI detector for diagnosis and follow up of the prostate cancer
, 2017 Prostate cancer is the most common disease in men and the second leading cause of death from cancer. Generic large imaging instruments used in cancer diagnosis have sensitivity, spatial resolution, and contrast inadequate for the task of imaging details ...
E. Monno +17 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
18F-FAC PET Visualizes Brain-Infiltrating Leukocytes in a Mouse Model of Multiple Sclerosis. [PDF]
, 2020 Brain-infiltrating leukocytes contribute to multiple sclerosis (MS) and autoimmune encephalomyelitis and likely play a role in traumatic brain injury, seizure, and stroke.
Chen, Bao Ying +6 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source