Results 81 to 90 of about 1,691,728 (255)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Studies on ToF-PET using Cherenkov radiation [PDF]

open access: yes, 2015
La tomografia ad emissione di positroni (PET) è una tecnica di imaging di medicina nucleare, utilizzata oggi diffusamente in ambito clinico. Essa fornisce immagini e informazioni fisiologiche dei processi funzionali all’interno del corpo.
La Rosa, Francesco
core  

A novel method for calibration and monitoring of time synchronization of TOF-PET scanners by means of cosmic rays

open access: yes, 2014
All of the present methods for calibration and monitoring of TOF-PET scanner detectors utilize radioactive isotopes such as e.g. $^{22}$Na or $^{68}$Ge, which are placed or rotate inside the scanner.
Bednarski, T.   +25 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

MODERN ISSUES OF ORGANIZING RADIO PHARM PREPARATIONS PRODUCTION BASED ON ⁶⁸GA

open access: yesРазработка и регистрация лекарственных средств, 2019
Functional diagnostics method (scintigraphy), connected with injection of radioactive isotopes with further getting of 2-D image by emitting radiation detection, is widely used in medicine.
O. A. Melnikova   +4 more
doaj  

Improving mechanical properties of recycled fibre-reinforced concrete through the use of magnetic water

open access: yesAdvances in Civil and Architectural Engineering
This study investigated the performance of Polyethylene terephthalate (PET), polypropylene, and steel fibres in concrete, utilizing both regular and magnetic water.
Mahdi Jangi   +2 more
doaj   +1 more source

Attenuation correction for brain PET imaging using deep neural network based on dixon and ZTE MR images

open access: yes, 2018
Positron Emission Tomography (PET) is a functional imaging modality widely used in neuroscience studies. To obtain meaningful quantitative results from PET images, attenuation correction is necessary during image reconstruction. For PET/MR hybrid systems,
Fakhri, Georges El   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

People and Pets in the COVID-19 Pandemic and the Cost-of-Living Crisis: Identifying Trends in the Intake, Adoption and Return of Companion Animals During Times of Uncertainty

open access: yesAnimals
Pet ownership is the most common form of human–animal interaction (HAI), is prevalent worldwide and confers benefits for the health and wellbeing of humans.
Lindsay Murray   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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