Results 91 to 100 of about 2,246,984 (309)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Multimodale Bildgebung in der pädiatrischen Onkologie [PDF]

open access: yes, 2013
The evaluation of multimodal imaging in paediatric oncology is the main theme of this thesis. Both published studies evaluate 18F-fluorodesoxyglucose positron emission tomography (18FFDG-PET) combined with an additional imaging modality in paediatric ...
Melzer, Henriette Ingrid
core   +1 more source

Feasibility of simultaneous PET-MR perfusion using a novel cardiac perfusion phantom

open access: yesEuropean Journal of Hybrid Imaging, 2017
Background PET-MR scanners are beginning to be employed for quantitative myocardial perfusion imaging. In order to examine simultaneous perfusion calculations, this work describes a feasibility study of simultaneous PET-MR of gadolinium-based contrast ...
Jim O’Doherty   +6 more
doaj   +1 more source

Approaches to PET Imaging of Glioblastoma

open access: yesMolecules, 2020
Glioblastoma multiforme (GBM) is the deadliest type of brain tumor, affecting approximately three in 100,000 adults annually. Positron emission tomography (PET) imaging provides an important non-invasive method of measuring biochemically specific targets
Lindsey R. Drake   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Conheça seu PET [PDF]

open access: yes, 2020
PET-Economia vem cumprindo o seu papel e contribuindo para a melhoria da graduação.
PET - Economia UFCG
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

The new generation of Long axial field of view PET scanners: comparison between United Imaging Explorer and Siemens Quadra [PDF]

open access: yes, 2022
openQuesta tesi è incentrata sull’analisi e lo studio delle nuove generazioni di macchinari diagnostici ad emissione di positroni proposte dalle aziende United Imaging e Siemens, che propongono un’innovativa e più completa concezione di esame di ...
MENEGAZZO, DAVIDE
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Sigma receptor ligands: novel applications in cancer imaging and treatment [PDF]

open access: yes, 2012
Sigma receptoren (subtypes sigma-1 en sigma-2) zijn unieke bindingsplaatsen die een aanzienlijk hogere expressie vertonen in kanker dan in gezond weefsel.
Rybczynska, Anna A.,   +1 more
core   +1 more source

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