Results 101 to 110 of about 528,168 (327)

A novel TOF-PET MRI detector for diagnosis and follow up of the prostate cancer

, 2017
Prostate cancer is the most common disease in men and the second leading cause of death from cancer. Generic large imaging instruments used in cancer diagnosis have sensitivity, spatial resolution, and contrast inadequate for the task of imaging details ...
E. Monno, F. Garibaldi, F. Giuliani, F. Santavenere, G. Carpinelli, H. Wegener, J. Tödter, K. Ziemons, L. Cosentino, M. Gricia, M. Lucentini, N. Clinthorne, P. Finocchiaro, P. Musico, R. Canese, S. Beging, S. Colilli, S. Majewski   +17 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Feasibility of simultaneous PET-MR perfusion using a novel cardiac perfusion phantom

European Journal of Hybrid Imaging, 2017
Background PET-MR scanners are beginning to be employed for quantitative myocardial perfusion imaging. In order to examine simultaneous perfusion calculations, this work describes a feasibility study of simultaneous PET-MR of gadolinium-based contrast ...
Jim O’Doherty, Eva Sammut, Paul Schleyer, James Stirling, Muhummad Sohaib Nazir, Paul K. Marsden, Amedeo Chiribiri   +6 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

PET-MR imaging using a tri-modality PET/CT-MR system with a dedicated shuttle in clinical routine [PDF]

, 2018
Tri-modality PET/CT-MRI includes the transfer of the patient on a dedicated shuttle from one system into the other. Advantages of this system include a true CT-based attenuation correction, reliable PET-quantification and higher flexibility in patient ...
Delso, Gaspar, Kuhn, Felix, Veit-Haibach, Patrick, von Schulthess, Gustav, Wiesinger, Florian   +4 more
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

NI-3 Magnetic resonance relaxometry for tumor cell density imaging for glioma: An exploratory study via 11C-methionine PET and its validation via stereotactic tissue sampling [PDF]

, 2021
Manabu Kinoshita, Masato Uchikoshi, Souichiro Tateishi, Shohei Miyazaki, Mio Sakai, Tomohiko Ozaki, Katsunori Asai, Yuya Fujita, Takahiro Matsuhashi, Yonehiro Kanemura, Eku Shimosegawa, Jun Hatazawa, Shin‐ichi Nakatsuka, Haruhiko Kishima, Katsuyuki Nakanishi   +14 more
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Liquid Xenon Detectors for Positron Emission Tomography

, 2011
PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve time ...
A J Stoessl, A Miceli, A Muennich, Agostinelli S, Amaudruz P, Angle J, Aprile E, D A Bryman, Doke T, F Benard, F Retiere, J P Martin, Krishnamoorthy S, L Kurchaninov, Martin J P, Neilson R, Oberlack U G, P Amaudruz, T J Ruth, V Sossi   +19 more
core   +1 more source