Results 101 to 110 of about 515,617 (283)

Liquid Xenon Detectors for Positron Emission Tomography

, 2011
PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve time ...
A J Stoessl, A Miceli, A Muennich, Agostinelli S, Amaudruz P, Angle J, Aprile E, D A Bryman, Doke T, F Benard, F Retiere, J P Martin, Krishnamoorthy S, L Kurchaninov, Martin J P, Neilson R, Oberlack U G, P Amaudruz, T J Ruth, V Sossi   +19 more
core   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

FDG-PET AND PET/CT - Part I

Indian Journal of Radiology and Imaging, 2007
Positron emission tomography (PET) with 18 F fluoro-deoxyglucose (FDG) is now an established functional imaging modality predominantly used in the work-up of several neoplastic diseases.
Amol M Takalkar, Ghassan El-Haddad, David L Lilien   +2 more
doaj   +1 more source

Accomplishments and challenges in stem cell imaging in vivo. [PDF]

, 2019
Stem cell therapies have demonstrated promising preclinical results, but very few applications have reached the clinic owing to safety and efficacy concerns.
Bose, Rajendran JC, Mattrey, Robert F
core  

PET imaging of HER-2-positive tumours [PDF]

, 2011
Laura Gilardi, Giovanni Paganelli
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Machine learning to identify suitable boundaries for band-pass spectral analysis of dynamic [ $$^{11}$$ 11 C]Ro15-4513 PET scan and voxel-wise parametric map generation

EJNMMI Research
Background Spectral analysis is a model-free PET quantification technique that treats the time-space signal as an impulse response to a bolus injection.
Zeyu Chang, Colm J. McGinnity, Rainer Hinz, Manlin Wang, Joel Dunn, Ruoyang Liu, Mubaraq Yakubu, Paul Marsden, Alexander Hammers   +8 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Quantification of porcine myocardial perfusion with modified dual bolus MRI – a prospective study with a PET reference

BMC Medical Imaging, 2019
Background The reliable quantification of myocardial blood flow (MBF) with MRI, necessitates the correction of errors in arterial input function (AIF) caused by the T1 saturation effect.
Minna Husso, Mikko J. Nissi, Antti Kuivanen, Paavo Halonen, Miikka Tarkia, Jarmo Teuho, Virva Saunavaara, Pauli Vainio, Petri Sipola, Hannu Manninen, Seppo Ylä-Herttuala, Juhani Knuuti, Juha Töyräs   +12 more
doaj   +1 more source

Breast Cancer and Aging: Understanding the Complex Relationship and Implications for Prevention and Screening

Aging and Cancer, EarlyView.
ABSTRACT Background Breast cancer is a multifactorial disease that affects many women worldwide. Age is the most important risk factor for breast cancer, with an increased incidence markedly after the age of 50. The relationships of aging to breast cancer have been thoroughly examined, and notable connections regarding various age‐related changes in ...
Mehran Radak, Armin Sharifi, Derek Richard, Hossein Fallahi   +3 more
wiley   +1 more source