Results 111 to 120 of about 528,168 (327)

DULDA: Dual-domain Unsupervised Learned Descent Algorithm for PET image reconstruction [PDF]

, 2023
Rui Hu, Yunmei Chen, Kyungsang Kim, Marcio Aloísio Bezerra Cavalcanti Rockenbach, Quanzheng Li, Huafeng Liu   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FDG-PET AND PET/CT - Part I

Indian Journal of Radiology and Imaging, 2007
Positron emission tomography (PET) with 18 F fluoro-deoxyglucose (FDG) is now an established functional imaging modality predominantly used in the work-up of several neoplastic diseases.
Amol M Takalkar, Ghassan El-Haddad, David L Lilien   +2 more
doaj   +1 more source

Castration-Resistant Prostate Cancer Bone Metastasis Response Measured by ¹⁸F-Fluoride PET After Treatment with Dasatinib and Correlation with Progression-Free Survival: Results from American College of Radiology Imaging Network 6687 [PDF]

, 2015
Evan Y. Yu, Fenghai Duan, Mark Muzi, Xuan Deng, Bennett B. Chin, Joshi J. Alumkal, Mary-Ellen Taplin, Jina Taub, Ben Herman, Celestia S. Higano, Robert K. Doot, Donna Hartfeil, Philip G. Febbo, David A. Mankoff   +13 more
openalex   +1 more source

AdaMSS: Adaptive Multi-Modality Segmentation-to-Survival Learning for Survival Outcome Prediction from PET/CT Images [PDF]

, 2023
Mingyuan Meng, Bingxin Gu, Michael Fulham, Shaoli Song, Dagan Feng, Lei Bi, Jinman Kim   +6 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Machine learning to identify suitable boundaries for band-pass spectral analysis of dynamic [ $$^{11}$$ 11 C]Ro15-4513 PET scan and voxel-wise parametric map generation

EJNMMI Research
Background Spectral analysis is a model-free PET quantification technique that treats the time-space signal as an impulse response to a bolus injection.
Zeyu Chang, Colm J. McGinnity, Rainer Hinz, Manlin Wang, Joel Dunn, Ruoyang Liu, Mubaraq Yakubu, Paul Marsden, Alexander Hammers   +8 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Quantification of porcine myocardial perfusion with modified dual bolus MRI – a prospective study with a PET reference

BMC Medical Imaging, 2019
Background The reliable quantification of myocardial blood flow (MBF) with MRI, necessitates the correction of errors in arterial input function (AIF) caused by the T1 saturation effect.
Minna Husso, Mikko J. Nissi, Antti Kuivanen, Paavo Halonen, Miikka Tarkia, Jarmo Teuho, Virva Saunavaara, Pauli Vainio, Petri Sipola, Hannu Manninen, Seppo Ylä-Herttuala, Juhani Knuuti, Juha Töyräs   +12 more
doaj   +1 more source