Results 51 to 60 of about 10,344 (216)

A Rare Cause of Prepubertal Gynecomastia: Sertoli Cell Tumor

Case Reports in Pediatrics, 2015
Prepubertal gynecomastia due to testis tumors is a very rare condition. Nearly 5% of the patients with testicular mass present with gynecomastia. Sertoli cell tumors are sporadic in 60% of the reported cases, while the remaining is a component of ...
Fatma Dursun, Şeyma Meliha Su Dur, Ceyhan Şahin, Heves Kırmızıbekmez, Murat Hakan Karabulut, Asım Yörük   +5 more
doaj   +1 more source

Clinical manifestations and STK11 germline mutations in Taiwanese patients with Peutz–Jeghers syndrome

Asian Journal of Surgery, 2018
Summary: Backgrounds: Clinical manifestations and molecular basis of Taiwanese patients with Peutz–Jeghers syndrome (PJS) were investigated to add the knowledge of phenotype and genotype of the disease.
Jy-Ming Chiang, Tse-Ching Chen
doaj   +1 more source

Peutz–Jeghers Syndrome which Develops into Descending Sigmoid Colon Adenocarcinoma

Indonesian Journal of Cancer, 2022
Introduction: Peutz–Jeghers Syndrome (PJS) is an autosomal dominant hereditary condition mainly characterized by hamartomatous gastrointestinal (GI) polyps. Medical treatment is often sought due to complications that arise from the polyps.
Abdul Mughni, Albert Eko Hendrawijaya, Meira Dewi Kusuma   +2 more
doaj   +1 more source

Incidental Colorectal Adenomas in Adolescents: Clinical Management, Genetic Evaluation, and Surveillance

Journal of Gastroenterology and Hepatology, EarlyView.
Adolescents with incidental colorectal adenomas require age‐conscious management balancing referral for genetic counseling with evidence‐based surveillance. This narrative review proposes a pragmatic clinical algorithm integrating adenoma characteristics, hereditary risk assessment, and guideline‐concordant follow‐up to support individualized ...
Brett J. Hoskins, Shlomi Cohen, Colleen B. Flahive, Isabel Rojas, Aparajita Singh, Thomas M. Attard   +5 more
wiley   +1 more source

The pattern of STK11 gene mutation and its phenotypical manifestation in patient with hamartomas polyposis

Біологічні студії, 2014
The clinical examination, genealogical and molecular genetic analysis of the probands and the risk group of three families with Peutz–Jeghers syndrome were carried out.
M. R. Lozynska, A. Plawski, I. V. Khavunka, N. M. Fomenko, L. Y. Lozynska   +4 more
doaj   +1 more source

Registro y seguimiento clínico de pacientes con síndrome de Peutz Jeghers en Valencia

Revista de Gastroenterología de México, 2020
Resumen: Introducción y objetivos: El síndrome de Peutz Jeghers (SPJ) es una enfermedad rara con herencia autosómica dominante, causada por una mutación germinal del gen STK11/LKB1, localizado en el cromosoma 19p13.3, que consiste en hiperpigmentación ...
F.A. Rodríguez Lagos, J.V. Sorlí Guerola, I.M. Romero Martínez, P. Codoñer Franch   +3 more
doaj   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system

Histopathology, Volume 88, Issue 7, Page 1295-1314, June 2026.
Changes and new entities in the 6th edition WCT of the digestive system, including structural, molecular, and diagnostic updates to standardize terminology and improve clinical relevance. Epithelial tumours are organized by site; neuroendocrine, mesenchymal and haematolymphoid tumours have dedicated chapters, with refined grading, redefined ...
Mark J Arends, Irene Esposito, Anthony J Gill, Ralph H Hruban, Joseph D Khoury, Motohiro Kojima, Elizabeth A Montgomery, Fatimah Abdulkareem, Fátima Carneiro, Guido Costamagna, Gregory Lauwers, Alexandros D Polydorides, Guido Rindi, Massimo Rugge, Peter Schirmacher, Amitabh Srivastava, James Yao, Jennelle C Hodge, James G Kench, Bharat Rekhi, Miguel Reyes‐Múgica, Antonia R Sepulveda, Chanjuan Shi, Pavitratha Puspanathan, Harshima Wijesinghe, Christine Giesen, Blanca Iciar Indave Ruiz, Dilani Lokuhetty, WCT standing editorial board, Iris D Nagtegaal, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle Hodge, James Kench, Joseph Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Múgica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia R Sepulveda, Chanjuan Shi, Gary Tse   +48 more
wiley   +1 more source

Síndrome de Peutz-Jeghers: tratamento da lentiginose oral com laser Alexandrita Peutz-Jeghers Syndrome: treatment of oral lentiginosis with Alexandrite laser

Anais Brasileiros de Dermatologia, 2003
Descreve-se o caso de uma paciente de 10 anos de idade, com síndrome de Peutz-Jeghers, que há oito anos apresentava manchas escuras nos lábios. As lesões da mucosa oral foram tratadas com laser de Alexandrita 755 nm, de pulso longo(3ms),com bons ...
Cristina Mansur, Leonora Mansur, Renata Côrtes Gonçalves, João Mansur, Aloísio Couri Gamonal, Rodolpho Valverde   +5 more
doaj   +1 more source

Unusual Presentation of Intussusception of the Small Bowel with Peutz Jeghers Syndrome: Report of a Case [PDF]

Journal of Clinical and Diagnostic Research, 2013
The Peutz Jeghers syndrome (PJS) is an autosomal dominant disorder which is characterised by hamartomatous polyposes of the gastrointestinal tract, melanin pigmentation of the skin and mucous membranes, and an increased risk for cancer. We are reporting
Ashish Shrivastava, Akshara Gupta, Achal Gupta, Jyoti Shrivastava   +3 more
doaj   +1 more source