Results 71 to 80 of about 10,344 (216)

Multigene Germline Panel Testing in Gastric Cancer Patients in a Portuguese Population

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Gastric cancer is a heterogeneous disease with both environmental and genetic determinants. While Multigene Germline Panel Testing (MGPT) increasingly reveals hereditary predisposition, the prevalence and clinical significance of germline variants in Portuguese gastric cancer patients tested through institutional MGPT programs ...
B. Mourato, B. Cordeiro, F. Costa Pinto, N. Pratas, H. Capote, I. Fronteira, M. Areia, R. Dinis   +7 more
wiley   +1 more source

Peutz-Jeghers Syndrome: A Case Report and Literature Review in Indonesia

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Background: Peutz-Jeghers Syndrome (PJS) is a rare hereditary polyposis syndrome that is autosomal dominant and has the main characteristics of hamartoma polyps, mucocutaneous pigmentation, and increased susceptibility to malignancy.
Kaka Renaldi, Yudha Friatna
doaj   +1 more source

Safety and efficacy of an enteroscopy-based approach in reducing the polyp burden in patients with Peutz–Jeghers syndrome: experience from a tertiary referral center

Therapeutic Advances in Gastrointestinal Endoscopy, 2020
Background: Patients with Peutz–Jeghers syndrome develop hamartomatous polyps in the small bowel, possibly causing anemia, intussusception, and obstruction.
Pablo Cortegoso Valdivia, Emanuele Rondonotti, Marco Pennazio   +2 more
doaj   +1 more source

LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases

MedComm, Volume 7, Issue 3, March 2026.
The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley   +1 more source

Colocolic Intussusception: A Case Report of an Uncommon Manifestation of Peutz-Jeghers Syndrome

مجله كليه طب الكندي
Peutz-Jeghers syndrome is a rare genetic disorder resulting from defects in signaling pathway regulation, marked by gastrointestinal hamartomas and mucocutaneous pigmentation.
Qasem Alyhari, Saleh Al-Wageeh, Faisal Ahmed, Hanan Mohammed, Noha Dahan, Asad Alhadi   +5 more
doaj   +1 more source

A Rare Case of Solitary Peutz Jeghers Type Hamartomatous Duodenal Polyp with Dysplasia! [PDF]

Journal of Clinical and Diagnostic Research, 2016
Solitary Peutz Jeghers (SPJ) type hamartomatous polyp is a rare and separate entity from classic Peutz Jeghers syndrome (PJS). A hamartomatous polyp without associated mucocutaneous pigmentations, any other gastrointestinal polyp or a family history of ...
Chetan Devendra Rathi, Dattatray Balasaheb Solanke, Nikita Lalitkumar Kabra, Meghraj Ananda Ingle, Prabha Dilip Sawant   +4 more
doaj   +1 more source

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature

Histopathology, Volume 88, Issue 4, Page 831-842, March 2026.
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci, Dario de Biase, Thais Maloberti, Agnese Orsatti, Thomas M Ulbright, Muhammad T Idrees, Esther Oliva, Kristine Cornejo, João Lobo, Kvetoslava Michalova, Maria Rosaria Raspollini, Sean R Williamson, Geert JLH van Leenders, Chia‐Sui Kao, Fiona Maclean, Ankur R Sangoi, Adeboye O Osunkoya, Michelangelo Fiorentino, Antonio De Leo, Giovanni Tallini, Andres Martin Acosta   +20 more
wiley   +1 more source

Multicenter survey on the use of device-assisted enteroscopy in Portugal [PDF]

, 2016
Background: Device-assisted enteroscopies (DAEs) are recent endoscopic techniques that enable direct endoscopic smallbowel evaluation. Objective: The objective of this article is to evaluate the implementation of DAEs in Portugal and assess the main ...
Almeida, N, Cardoso, C, Cardoso, H, Cotter, J, Ferreira, S, Figueiredo, P, Marcos-Pinto, R, Marques, M, Mascarenhas-Saraiva, M, Mão-de-Ferro, S, Pinho, R, Rodrigues, A, Rosa, B, Salgado, M, Vilas-Boas, G   +14 more
core   +2 more sources

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source