Results 61 to 70 of about 5,377 (175)

Outcomes of ‘in‐house’ genetic testing within a specialist hereditary colorectal cancer registry

Colorectal Disease, Volume 28, Issue 10, October 2026.
Abstract Aims Approximately 5%–10% of colorectal cancer (CRC) cases are due to known Mendelian syndromes. This study aimed to report the diagnostic yield of constitutional genetic testing, alongside clinicopathological factors for hereditary CRC, within a specialised National Bowel Hospital, and outside traditional genetics referral pathways.
Manasawee Srisuttayasathien, Victoria Cuthill, Menna Hawkins, Ashish Sinha, Susan Clark, Andrew Latchford, Kevin J. Monahan   +6 more
wiley   +1 more source

A novel classification of testicular sex cord‐stromal tumours from the Testicular Sex Cord‐Stromal Tumour (TESST) group: a collaboration of the Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP)

Histopathology, Volume 89, Issue 4, Page 638-649, October 2026.
The TESST classification of testicular sex cord‐stromal tumours was agreed upon by consensus based on the best available evidence. The picture shows the members of the TESST group and delegates of GUPS and ISUP present in‐person at the first meeting of the group held at Johns Hopkins Hospital (Baltimore, 2024). Aims Testicular sex cord‐stromal tumours (
Andres M. Acosta, Felix Bremmer, John C. Cheville, Maurizio Colecchia, Eva Comperat, Kristine Cornejo, Dilek E. Baydar, Anthony J. Gill, Maria del Pilar Gonzalez‐Peramato, Sounak Gupta, Michelle S. Hirsch, Muhammad T. Idrees, Chia‐Sui Kao, Fiona MacLean, Andres Matoso, Rohit Mehra, Santosh Menon, Kvetoslava Michalova, Sambit K. Mohanty, Miguel Reyes‐Mugica, Maria Rosaria Raspollini, Ankur R. Sangoi, Lynette M. Sholl, Stephanie Siegmund, Satish K. Tickoo, Toyonori Tsuzuki, Thomas M. Ulbright, Sean R. Williamson, Asli Yilmaz, Daniel M. Berney   +29 more
wiley   +1 more source

Síndrome de Peutz-Jeghers: relato de caso

Revista do Colégio Brasileiro de Cirurgiões
Peutz-Jeghers syndrome (PJS) is a dominant autosomal inherited disorder characterized by intestinal hamartomatous polyps in association with mucocutaneous melanocytic maculae.
Aderivaldo Coelho de Andrade, Edílson Carvalho Júnior, Karoline da Silva Dantas, Jocerlano Santos de Sousa, Ricardo Keyson Paiva de Morais   +4 more
doaj   +1 more source

Peutz-Jeghers syndrome: A circumventable emergency

Indian Journal of Dermatology, 2018
Peutz-Jeghers syndrome (PJS) is characterized by multiple hamartomatous polyps in the gastrointestinal tract and mucocutaneous pigmentation. Here we present, a case of multiple gastrointestinal hamartomatous polyps in a 22-year-old male who had been operated for intestinal obstruction due to ileocolic intussusception.
Sourav Choudhury, Anupam Das, Priyankar Misra, Udipta Ray, Sujata Sarangi   +4 more
openaire   +3 more sources

STK11 Mutations and Deletions Define an Aggressive Molecular Subgroup of Cervical Adenocarcinoma

Cancer Medicine, Volume 15, Issue 9, September 2026.
STK11 alterations, including mutations, focal deletions, and structural disruption of chromosome 19p, define a distinct molecular subgroup of cervical adenocarcinoma associated with younger age at diagnosis, poorer survival, and reduced benefit from immune checkpoint inhibitors, supporting improved molecular classification and future precision ...
Emma W. Robinson, Elisabeth A. Murphy, Anaseidy Albanez, Sonam Tulsyan, Hong Lou, Yi Xie, Weiyin Zhou, Qian Yang, Tawnjerae Joe, Tongwu Zhang, Jia Liu, Wen Luo, Dongjing Wu, Herbert Higson, Mathias Viard, Mary Carrington, Matthew Oberley, Hesler Morales, Lisa Mirabello, Enrique Alvirez, Roberto Orozco, Eduardo Gharzouzi, Michael Dean   +22 more
wiley   +1 more source

Peutz-Jeghers Syndrome: A Case Report and Literature Review in Indonesia

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Background: Peutz-Jeghers Syndrome (PJS) is a rare hereditary polyposis syndrome that is autosomal dominant and has the main characteristics of hamartoma polyps, mucocutaneous pigmentation, and increased susceptibility to malignancy.
Kaka Renaldi, Yudha Friatna
doaj   +1 more source

Real‐Time AI‐Assisted Detection of Colonic Lesions Using the iIDEAS Intelligent‐C Module: A Prospective Single‐Center Validation Study

JGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Aims Colorectal cancer (CRC) remains a major cause of cancer mortality, with up to 26% of adenomas missed on conventional colonoscopy. Artificial intelligence (AI)–based computer‐aided detection (CADe) systems may reduce these miss rates.
Hardik Rughwani, Rajat Garg, Sana Fathima Memon, Chung Kwong Yeung, Biji Sreedhar, Kwun Ping Lai, Rajendra Patel, Nitin Jagtap, Syed Jameel Hussain, Mohammed Sanny, Rakesh Kalapala, D. Nageshwar Reddy   +11 more
wiley   +1 more source

Colocolic Intussusception: A Case Report of an Uncommon Manifestation of Peutz-Jeghers Syndrome

مجله كليه طب الكندي
Peutz-Jeghers syndrome is a rare genetic disorder resulting from defects in signaling pathway regulation, marked by gastrointestinal hamartomas and mucocutaneous pigmentation.
Qasem Alyhari, Saleh Al-Wageeh, Faisal Ahmed, Hanan Mohammed, Noha Dahan, Asad Alhadi   +5 more
doaj   +1 more source

Safety and efficacy of an enteroscopy-based approach in reducing the polyp burden in patients with Peutz–Jeghers syndrome: experience from a tertiary referral center

Therapeutic Advances in Gastrointestinal Endoscopy, 2020
Background: Patients with Peutz–Jeghers syndrome develop hamartomatous polyps in the small bowel, possibly causing anemia, intussusception, and obstruction.
Pablo Cortegoso Valdivia, Emanuele Rondonotti, Marco Pennazio   +2 more
doaj   +1 more source

Urgent double-balloon enteroscopy for reduction of jejuno-jejunal intussusception and polypectomy in Peutz-Jeghers syndrome

Journal of Pediatric Surgery Case Reports, 2020
A 13-year-old girl presented with sudden-onset colicky abdominal pain and biliary vomiting. She was diagnosed with Peutz-Jeghers syndrome 2 months previously based on mucocutaneous pigmentation and hamartomatous polyposis.
Yoshiko Nakayama, Sawako Kato, Shingo Kurasawa, Reina Nakamura, Tomoaki Suga, Masahiro Kurozumi   +5 more
doaj   +1 more source