Results 131 to 140 of about 38,799 (355)

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

Advanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández, Mariarosaria De Simone, Yilian Fernández‐Afonso, Daniel Garcia‐Gonzalez, Pablo Martínez‐Vicente, Thomas van Zanten, Raluca M. Fratila, Maria Moros   +7 more
wiley   +1 more source

Integrated analysis of per- and polyfluoroalkyl substances and plasma lipidomics profiles in multi-ethnic Asian subjects for exposome research

Environmental Health
Background Perfluoroalkyl and polyfluoroalkyl substances (PFAS) exposure has been associated with metabolic diseases, however, the underlying molecular pathogenesis remains to be understood.
Kothandaraman Narasimhan, Vaitheeswari, Ellie Choi, Nisha Suyien Chandran, Johan G. Eriksson, Anne K. Bendt, Federico Torta, Sartaj Ahmad Mir   +7 more
doaj   +1 more source

Is a Seismic Shift in the Landscape of PFAS Uses Occurring? [PDF]

Martin Scheringer, Ian T. Cousins, Gretta Goldenman   +2 more
openalex   +1 more source

Enhanced PFAS adsorption with N-doped porous carbon beads from oil-sand asphaltene

, 2023
Bożena Czech, Bijan Nasri‐Nasrabadi, Agnieszka Krzyszczak, Ilona Sadok, Mirabbos Hojamberdiev, Ramdayal Yadav, Kamyar Shirvanimoghaddam, Minoo Naebe   +7 more
openalex   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Maternal transfer and sex-differences in brain bioaccumulation for Northern bobwhite quail (Colinus virginianus) exposed to per- and poly-fluoroalkyl substances

Ecotoxicology and Environmental Safety
Per- and poly-fluoroalkyl substances (PFAS) are highly persistent chemicals commonly found in surface protectants, and class B aqueous film forming foams (AFFF), and many other consumer and industrial products. As a result of their widespread application
Kenneth N. Kikanme, Adcharee Karnjanapiboonwong, Rameshkumar Angappan, Nicole M. Dennis, Farzana Hossain, Jamie G. Suski, Christopher J. Salice, Todd A. Anderson   +7 more
doaj   +1 more source

Growth Management Policies for Exurban and Suburban Development: Theory and an Application to Sonoma County, California [PDF]

This study examines the effectiveness of growth management policies on influencing future patterns of exurban and suburban development. We initially estimate a spatially explicit model of residential development with parcel data in Sonoma County ...
Berck, Peter, Newburn, David A.
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Diverse PFAS produce unique transcriptomic changes linked to developmental toxicity in zebrafish

Frontiers in Toxicology
Per- and polyfluoroalkyl substances (PFAS) are a widespread and persistent class of contaminants posing significant environmental and human health concerns. Comprehensive understanding of the modes of action underlying toxicity among structurally diverse
Yvonne Rericha, Yvonne Rericha, Lindsey St. Mary, Lindsey St. Mary, Lisa Truong, Lisa Truong, Ryan McClure, J. Kainalu Martin, Scott W. Leonard, Preethi Thunga, Michael T. Simonich, Katrina M. Waters, Katrina M. Waters, Jennifer A. Field, Robyn L. Tanguay, Robyn L. Tanguay   +15 more
doaj   +1 more source

Emerging Contaminants Such as Perfluorinated Compounds: Toxicity and Oxidative Stress [PDF]

, 2017
Irato, P., Tallandini, L., Trabucco, S.
core   +1 more source