Results 151 to 160 of about 10,658 (266)

Anion exchange beads for PFAS capture using a polymerization-induced microphase separation approach.

RSC Appl Polym
Arshad A, Back J, Faber KA, Arnold WA, Bühlmann P, Hillmyer MA.   +5 more
europepmc   +1 more source

Identification and quantification of PFAS in the tap water of a French City, Besançon. [PDF]

Environ Monit Assess
Crini G, Mongioví C, Bradu C, Audonnet N, Yquel S, Lacalamita D.   +5 more
europepmc   +1 more source

PFAS and their Alternatives

Invited Keynote, ALGA: PFAS Management into the Future, March 14, 2024, Sydney, Australia.
openaire   +2 more sources

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

Sorbent Intervention to Reduce Per- and Polyfluoroalkyl Substances (PFAS) in Maternal Reproductive Tissues and Transgenerational Translocation in Sprague-Dawley Rats. [PDF]

J Hazard Mater Adv
Oladele JO, Rivenbark KJ, Adekomi DA, Phillips TD, Wang M.   +4 more
europepmc   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

PFAS exposure and reproductive dysfunction: implications for outcomes in assisted reproductive technologies. [PDF]

Front Endocrinol (Lausanne)
Shu X, Zhou WJ, Zhang T, Ye JF, Zhao YJ, Gu CJ, Yu YY, Li MQ.   +7 more
europepmc   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

Advanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du, Yinming Li, Ziyue Li, Yuedan Wang, Shaopeng Li, Yijie Wang, Yingying Qu, Bingyang Lv, Ying Li, Ting Chen, Yu Zhou, Xuan Xiao   +11 more
wiley   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

Advanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi, Hao Jia, Jianfei Dong, Linhao Li, Jingqi Cao, Xun Chen, Zhenzhen Jia, Jing Na, Zhijie Yang, Xinyuan Chen, Yubo Fan, Shuhua Yue, Lisha Zheng   +12 more
wiley   +1 more source

Environmental Exposure to Emerging Per- and Polyfluoroalkyl Substances and Cardiovascular Diseases: A Mixture Analysis. [PDF]

Health Sci Rep
Ripon RK, Hassan MM, Volquez M, Sola S, Saunik S, Govind S, Prasad N.   +6 more
europepmc   +1 more source