Results 161 to 170 of about 31,589 (307)

Development of a Risk Matrix for Assessing PFAS in Food Packaging. [PDF]

Foods
Wack K, Apprich S, Bergmair J, Tacker M.
europepmc   +1 more source

Emerging Contaminants Such as Perfluorinated Compounds: Toxicity and Oxidative Stress [PDF]

, 2017
Irato, P., Tallandini, L., Trabucco, S.
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Presence of Legacy and Emerging PFAS in Human Liver Specimens Banked in the United States from 2000 to 2024. [PDF]

Environ Sci Technol
Agudelo Areiza J, Becanova J, Vojta S, Ganglbauer J, Apte U, Brunetti L, Kumer S, Haque F, Kim E, Sunderland EM, Lohmann R, Fischer FC, Slitt A.   +12 more
europepmc   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Prediction of endometrial tissue PFAS concentrations using serum levels, demographic, and reproductive factors: Findings from the Investigating Mixtures of Pollutants and Endometriosis in Tissue (IMPLANT) study. [PDF]

Environ Epidemiol
Fuzak Nunziato MK, Chin HB, Krall JR, Reynolds M, Kannan K, Pollack AZ.   +5 more
europepmc   +1 more source

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

Advanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee, Oliver James, Gaeun Jung, Doyun Lee, Yee‐Joon Kim   +4 more
wiley   +1 more source

An Ecosystem-Scale Model of PFAS Dynamics in Stream-to-Riparian Food Webs. [PDF]

Environ Sci Technol
Campbell KS, Wesner JS, Walters DM, Helton AM, Baranovic AM, Agrawal A, Stricker CA, Provatas AA, Kraus JM, Briggs MA, Brandt JE.   +10 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Per- and polyfluoroalkyl substances (PFAS) and heavy metals in the egg of peregrine falcon (Falco peregrinus) populations in West England, United Kingdom. [PDF]

Ecotoxicology
Ozaki S, Chaplow JS, Dodd B, Grant H, Pereira MG, Potter E, Sale RG, Sleep D, Thacker S, Watson SJ, Walker LA, Qassim SM.   +11 more
europepmc   +1 more source