Results 31 to 40 of about 29,031 (266)
Molecular dynamics-based methodological approach to clarify perfluorooctanoic acid binding on human serum albumin [PDF]
Journal of the Serbian Chemical SocietyPerfluorooctanoic acid (PFOA) is a persistent environmental contaminant that binds strongly to human serum albumin (HSA), influencing its distribution and toxicokinetics.
Đurđević-Đelmaš Aleksandra M. +3 more
doaj +1 more source
Emerging and legacy PFAS and cytokine homeostasis in women of childbearing age
Scientific Reports, 2022 Per- and polyfluoroalkyl substances (PFAS) are widespread chemicals. Legacy PFAS have been phased out of production in most developed countries and emerging PFAS (short-chain PFAS and polyfluorinated compounds) are used as legacy PFAS alternatives.
Min Nian +5 more
doaj +1 more source
Methods for the PFAS analysis proposed in 2022: literature search
, 2022 openRicerca bibliografica su metodi di analisi, essenzialmente cromatografici con HRMS, proposti nel 2022 per determinare i PFAS in diverse ...
PERUZZI, NICOLÒ
core
Quantification of PFAS in soils treated with biosolids in ten northeastern US farms
Scientific ReportsThis study, one of the few conducted to date on working farms in the US, examined per- and polyfluoroalkyl substances (PFAS) contamination in 10 farms treated with biosolids using a paired control-treatment approach.
Diana Oviedo-Vargas +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Open ChemistryPer- and polyfluoroalkylated substances (PFAS) are a group of anthropogenic chemicals used in a multitude of applications. Nevertheless, PFAS are considered emerging contaminants, posing significant threats to human health as a consequence of their ...
Tzanetou Evangelia N. +3 more
doaj +1 more source
Per- and polyfluoroalkyl substances (PFAS) in PubChem: 7 million and growing [PDF]
, 2023 Per- and polyfluoroalkyl substances (PFAS) are of high concern, with calls to regulate these as a class. In 2021, the Organisation for Economic Co-operation and Development (OECD) revised the definition of PFAS to include any chemical containing at least
Jian, Zhang +5 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2022 The number of poly- and perfluoroalkyl substances (PFAS) and their sources, fates, and avenues of transport is vast. With every new discovery, a new question arises regarding the impact they are having on the environment.
Li, Shu-Guang +5 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source