Results 81 to 90 of about 28,141 (248)

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The increasing incidence of inflammatory bowel disease (IBD) in paediatric populations underscores the importance of effective management strategies. Anti–tumor necrosis factor (anti‐TNF) agents, such as infliximab (IFX) and adalimumab (ADL), are key treatments for inducing and maintaining remission in IBD, but many patients ...
Karlotta Pauline Hubert   +2 more
wiley   +1 more source

PGAS for (In)coherent Manycore Systems

open access: yes, 2021
As the architectural walls drive the number of parallel cores in multicore systems up, it becomes harder to maintain cache coherence across all of the physical memory and all cores. On the other hand, even given a performant cache-coherent system, the unavoidable non-uniform memory (NUMA) and non-uniform cache (NUCA) architectures make programming for ...
openaire   +2 more sources

Use of Patient Reported Outcome Measurements Information in Clinical Practice in Spain for the Clinical Management of Psoriasis Patients—Summer Project

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Routine collection of patient perspectives about psoriasis and its treatment through patient reported outcome measurements (PROMs), alongside clinician reported outcome measurements (CROMs), may improve clinical outcomes and facilitate shared decision making.
Jaime Notario   +7 more
wiley   +1 more source

Persistently different patterns of patient’s global assessment of health in rheumatoid arthritis are associated with pain and impaired function more than with inflammation: an inception cohort study over 15 years

open access: yesRMD Open
Objective To assess patient’s self-reported global assessment of health (PGA) in relation to inflammation, pain and disability in patients with rheumatoid arthritis (RA).Methods Data were obtained from the Better Anti-Rheumatic PharmacOTherapy early RA ...
Sofia Ajeganova   +3 more
doaj   +1 more source

G2‐PASE: A Novel, Rapid, and Reliable Measure of Plaque Psoriasis Severity

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background The Psoriasis Area and Severity Index (PASI), a composite measure of plaque psoriasis disease severity, is commonly used to determine treatment eligibility and response, but is time consuming for every‐day clinical use. The Gulliver‐Gestalt‐Psoriasis Area Severity Estimate (G2‐PASE) was developed to approximate PASI scores using ...
Wayne P. Gulliver   +10 more
wiley   +1 more source

Residual Disease in Adult Psoriasis‐Treated Patients: Frequency, Clinical Aspects, and Management. A Survey Among Dermatologists

open access: yesJEADV Clinical Practice, EarlyView.
Abstract Background In moderate‐to‐severe psoriasis, residual lesions can be defined as “psoriasis lesions that persist despite well‐managed treatment, and which do not necessarily justify intensification or a change in treatment.” Residual lesions are accepted by guidelines and clinical trials.
Emmanuel Mahé   +4 more
wiley   +1 more source

Latanoprostene Bunod 0.024% in Patients with Open-Angle Glaucoma Switched from Prior Pharmacotherapy: A Retrospective Chart Review

open access: yesClinical Ophthalmology
Constance O Okeke,1 Nora Lee Cothran,2 Desirae A Brinkley,3 Kamran Rahmatnejad,4 Frank J Rodiño,5 James E Deom6 1Virginia Eye Consultants/CVP, Norfolk, VA, USA; 2The Eye Institute of West Florida, Largo, FL, USA; 3Eye Specialty Group, Memphis, TN, USA ...
Okeke CO   +5 more
doaj  

Clinical study of the posterior gastric artery and the lymph nodes around it in patients with gastric cancer

open access: yesWorld Journal of Surgical Oncology
Objectives This study aims to gather and analyze the anatomical characteristics of the posterior gastric artery (PGA), investigate the presence and metastasis of lymph nodes around the PGA in patients with gastric cancer.
Kexin Wang   +6 more
doaj   +1 more source

A Cross‐Sectional Survey Study Assessing the Quality of Life and Sleep in Spanish Psoriasis Patients

open access: yesJEADV Clinical Practice, EarlyView.
Psoriasis impacts quality of life (QOL) and sleep (QOS), yet dermatology assessments often do not evaluate sleep. The Short‐form health survey (SF‐36) and Pittsburg sleep quality index (PSQI) further investigated patients’ QOL and QOS. Particularly women, unemployed patients, and those that use sleep medications had worse QOS and QOL.
Gabriela Piñero‐Crespo   +4 more
wiley   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

open access: yesMacromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani   +6 more
wiley   +1 more source

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